Oct 28, 2024 · Klinefelter syndrome, also known as XXY syndrome, is a condition in boys and men that’s caused by an extra X chromosome. It can affect physical and mental development.

Klinefelter syndrome (KS), also known as 47,XXY, is a chromosome anomaly where a male has an extra X chromosome. [10] These complications commonly include infertility and small, poorly functioning testicles (if present).

Nov 12, 2023 · The syndrome describes males with tall stature, small testes, gynecomastia, and azoospermia. The precise genetic etiology of supernumerary X chromosomes (47,XXY) was identified in 1959. Extra X chromosomes lead to testicular hyalinization, fibrosis, and hypofunction, resulting in genital abnormalities, usually hypogonadism, and infertility.

It's also called XXY because they have an extra X chromosome in most or all their cells. Usually, a person has 46 chromosomes in each cell, divided into 23 pairs, which includes two sex chromosomes. Half the chromosomes are inherited from …

Apr 24, 2023 · Yes, sometimes the genitalia of a baby who has intersex traits is noticeably different. Here are some possibilities: But the baby’s genitalia may also look completely male or completely female. In...

Mar 4, 2025 · XXY syndrome, also known as Klinefelter syndrome (KS), is a genetic condition characterized by the presence of an extra X chromosome (47, XXY). Humans have 22 pairs of numbered chromosomes and one pair of sex chromosomes, resulting in a …

Klinefelter syndrome, also called 47,XXY, is a chromosomal condition that affects male development. The signs and symptoms of Klinefelter syndrome vary. In some cases, the features are so mild that the condition is not diagnosed until puberty or adulthood.

Most men are born with a pair of XY chromosomes, while most females are born with pair of XX chromosomes. Klinefelter syndrome occurs when a male is born with an extra X chromosome. Thus a male with Klinefelter has XXY instead of the usual XY pair.

Klinefelter syndrome (47, XXY karyotype) is the spectrum of phenotypic features resulting from a sex chromosome complement that includes two or more X chromosomes and one Y chromosome (Figure 135-1).

Feb 14, 2024 · Klinefelter Syndrome (KS): chromosomal disorder with karyotype 47, XXY, affects 1.5 per 1000 live-born males. Aetiology: extra X chromosome due to meiotic non-disjunction or mosaicism; longer CAG repeats in androgen receptor gene correlate with severity. Risk factor: advanced maternal age.