
Virus-like particle - Wikipedia
Virus-like particles (VLPs) are molecules that closely resemble viruses, but are non-infectious because they contain no viral genetic material. They can be naturally occurring or synthesized through the individual expression of viral structural proteins, which can then self assemble into the virus-like structure.
Virus-like particles: preparation, immunogenicity and their …
Viral-like particles (VLPs) are nanoscale structures made up of assembled viral proteins that lack viral genetic material and are therefore non-infectious [1]. VLPs are dispersed nanomaterials that can be produced in a variety of systems, including mammals, plants, insects, and bacteria.
Virus-like Particles: Fundamentals and Biomedical Applications
Virus-like particles (VLPs) are self-assembled nanoparticles whose intrinsic properties, such as heterogeneity, and highly ordered structural organization are exploited to prepare vaccines; imaging agents; construct nanobioreactors; cancer treatment approaches; or …
Virus-Like Particles: Revolutionary Platforms for Developing …
Jan 22, 2022 · Engineered VLP-forming human or animal virus capsid proteins expressed in plant cells include human norovirus CP, HPV L1 protein, hepatitis B core and surface antigens, HIV Gag polyprotein, and HA protein of influenza virus (Rybicki, 2020).
Virus-like particle vaccinology, from bench to bedside
Aug 12, 2022 · Virus-like particles (VLPs) have become key tools in biology, medicine and even engineering. After their initial use to resolve viral structures at the atomic level, VLPs were rapidly...
Advances and challenges in enveloped virus-like particle (VLP) …
Virus-like particles (VLPs) are highly organized particles that self-assemble from viral structural proteins. Like parental viruses, VLPs can be either non-enveloped or enveloped and can be produced in different expression systems depending on their complexity.
Virus-Like Particle - an overview | ScienceDirect Topics
Virus-like particle (VLP) is a nanostructure with self-assembly feature that contains structural proteins of virus. Molecular and morphological characteristics of VLP are similar to authentic viruses.
Virus-Like Particles (VLPs) - Creative Diagnostics
Virus-like particles (VLPs) are hollow protein particles that are similar in shape to natural virus particles and are self-assembled by one or more structural proteins of viruses. The diameter of VLPs is about 20~200nm, which has a regular spatial structure and superior biocompatibility.
Virus-like particles: preparation, immunogenicity and their roles …
Feb 25, 2021 · Viral-like particles (VLPs) are nanoscale structures made up of assembled viral proteins that lack viral genetic material and are therefore non-infectious [1]. VLPs are dispersed nanomaterials that can be produced in a variety of systems, including mammals, plants, insects, and …
Virus-like Particle (VLP) Vaccine Bioprocessing and
VLPs provide a high immunogenic response because of their high-density display of epitopes, the capacity to present multiple proteins to the immune system, and their size (typically around 40 nm; influenza VLP is 80–120 nm), which seems to be optimal for uptake by dendritic cells.