Sep 3, 2024 · Total metabolic tumor volume (TMTV) is prognostic in lymphoma. However, cutoff values for risk stratification vary markedly, according to the tumor delineation method used. We aimed to create a standardized TMTV benchmark dataset allowing TMTV to be tested and applied as a reproducible biomarker.

High baseline TMTV (±ECOG) was a strong prognosticator of inferior PFS and OS in REMARC patients post-R-CHOP, irrespective of maintenance. Abstract. Early identification of ultra-risk diffuse large B-cell lymphoma (DLBCL) patients is needed to …

The aim of this study was to explore the prognostic value of total metabolic tumor volume (TMTV) at baseline 18F-FDG PET/CT in patients diagnosed with peripheral T-cell lymphoma (PTCL). Eighty-four newly diagnosed PTCL patients who underwent ...

Nov 5, 2024 · Total metabolic tumor volume (TMTV) derived from positron emission tomography/computed tomography (PET/CT) data has been shown to serve as an accurate tumor burden surrogate and be associated with outcomes in FL (Cottereau et al. Ann Oncol 2024).

Jan 1, 2024 · Baseline TMTV is a strong prognostic factor of POD24 and PFS in advanced FL, even in the era of antibody maintenance. SUV max was not predictive of PFS in either treatment arm. TMTV combined with FLIPI score identified a subgroup of patients (16%) at high risk of relapse with a 6-year PFS of 41.0%.

High total metabolic tumor volume (TMTV), computed from baseline 18 F-fluorodeoxyglucose–positron emission tomography (PET), is associated with shorter progression-free survival (PFS), but circulating tumor cells (CTCs) and cell-free DNA (cfDNA) may also reflect tumor burden and be of prognostic value.

Aug 1, 2024 · We aimed to create a standardized TMTV benchmark dataset allowing TMTV to be tested and applied as a reproducible biomarker. Methods: Sixty baseline 18F-FDG PET/CT scans were identied with a range of disease distributions (20 follicular, 20 Hodgkin, and 20 diffuse large B-cell lymphoma).

Mar 14, 2025 · The TNM staging system demonstrates robust prognostic utility in patients with LUAD, while the incorporation of baseline TMTV may offer additional risk stratification within distinct TNM stages.

Nov 5, 2024 · Total metabolic tumor volume (TMTV) derived from positron emission tomography/computed tomography (PET/CT) data has been shown to serve as an accurate tumor burden surrogate and be associated with outcomes in FL (Cottereau et al. Ann Oncol 2024).

In this study, we propose a two-step cascaded segmenta-tion approach to facilitate TMTV quantification and efec-tively handle the variability in lesion sizes and locations in lymphoma cases.