Thebaine (paramorphine), also known as codeine methyl enol ether, is an opiate alkaloid, its name coming from the Greek Θῆβαι, Thēbai (Thebes), an ancient city in Upper Egypt. A minor constituent of opium, thebaine is chemically similar to both morphine and codeine, but has stimulatory rather than depressant effects.

Thebaine is a morphinane alkaloid and an organic heteropentacyclic compound. It is functionally related to an oripavine. It is a conjugate base of a thebaine (1+). Thebaine is a DEA Schedule II controlled substance. Substances in the DEA Schedule II have a high potential for abuse which may lead to severe psychological or physical dependence.

La tebaína es uno de los numerosos alcaloides presentes en el opio. Químicamente similar a la codeína y a la morfina, se usa principalmente para crear derivados sintéticos, como la oxicodona y la naloxona. La tebaína fue descubierto por Pierre Joseph Pelletier en 1833 la estructura fue aclarada por Clemens Schöpf.

Thebaine is a naturally occurring alkaloid derived from opium. Thebaine has little analgesic action but is a precursor to several important 14-OH agents such as oxycodone and naloxone. A few derivatives of thebaine are more than 1000 times as potent as morphine (e.g., etorphine).9.

Tebaína (paramorfina), también conocida como codeína metil enol éter, es un alcaloide opiáceo, cuyo nombre proviene del griego Θῆβαι, Thēbai (Tebas), una ciudad antigua en el Alto Egipto. Un componente menor del opio, la tebaína es químicamente similar tanto a la morfina como a la codeína, pero tiene efectos estimulantes en lugar de depresores.

Jun 24, 2021 · Natural and synthetic Thebaine derivatives are used as “starting material” in some medications to aid in absorption. It can be found among a long list of compounds in a variety of prescription Opioids, including Buprenorphine, Oxycodone, Oxymorphone, and Naloxone.

Mar 30, 2020 · However, available limited data indicate that thebaine exhibits a higher acute toxic potential than morphine. Therefore, exposure to thebaine by consumption of poppy seed-containing food could pose a health risk.

The most practical synthetic routes to the preparation of as important pharmaceuticals as oxycodone, naloxone, naltrexone, nalbuphine and buprenorphine have utilized the alkaloid, thebaine, as a starting material.

Jun 3, 2014 · La tebaína es un alcaloide que se obtiene del opio, conocido por su estructura cristalizable. A diferencia de la morfina, su efecto narcótico es menor, lo que la hace interesante en el ámbito de la química y la medicina.

La tebaina (C 19 H 21 N O 3) è uno dei numerosi alcaloidi contenuti nell'oppio, chimicamente prossimo a morfina e codeina ma più tossico, e viene utilizzato principalmente per creare derivati sintetici quali ossicodone, naloxone (antagonizzante …