TIMP1 - Wikipedia
TIMP metallopeptidase inhibitor 1, also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein with a molecular weight of 28 kDa. [5] TIMP1 is expressed from several …
TIMP1 Gene - TIMP Metallopeptidase Inhibitor 1
Mar 30, 2025 · TIMP1 (TIMP Metallopeptidase Inhibitor 1) is a Protein Coding gene. Diseases associated with TIMP1 include Oral Submucous Fibrosis and Conjunctivochalasis. Among its …
Cytokine functions of TIMP-1 - PubMed
Recent studies on TIMP-1's cytokine functions have identified complex regulatory networks involving a specific surface receptor and subsequent signaling pathways including miRNA …
TIMP-1 is a novel ligand of Amyloid Precursor Protein and …
Feb 6, 2023 · The emerging cytokine tissue inhibitor of metalloproteinases-1 (TIMP-1) correlates with the progression of inflammatory diseases, including cancer. However, the effects of TIMP …
Recognizing the Molecular Multifunctionality and Interactome of TIMP-1
We propose here that this multifunctionality and the remarkably large interactome explain the diverse biological consequences of TIMP-1 expression in health and disease. Keywords: …
Tissue Inhibitor of Matrix Metalloproteinases-1 Knockdown Suppresses ...
Tissue inhibitor of metalloproteinases-1 (TIMP-1) is a multifunctional matrix metalloproteinase, and it is involved in the regulation of cell proliferation and apoptosis in various cell types. …
TIMP-1 and its potential diagnostic and prognostic value in …
In this review, we summarized the current knowledge of TIMP-1 in several pulmonary diseases namely, acute lung injury (ALI)/acute respiratory distress syndrome (ARDS), pneumonia, …
TIMP-1 is an activator of MHC-I expression in myeloid ... - Nature
May 22, 2024 · Primary human and bone-marrow-derived DCs secrete TIMP-1, which notably increases MHC-I expression in classical type 1 dendritic cells (cDC1), especially under …
Cut loose TIMP-1: an emerging cytokine in inflammation - Cell Press
Sep 23, 2022 · From clinical evidence, TIMP-1 emerges as an important regulator of inflammatory processes. TIMP-1 is detected, at elevated levels, in the blood of patients with an …
Recognizing the Molecular Multifunctionality and Interactome of TIMP-1
Sep 19, 2018 · TIMP-1 is a two-domain protein with multiple functions, and the list of its interaction partners has rapidly expanded in recent years. This review develops the first …