Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane in eukaryotic cells. Spectrin forms pentagonal or hexagonal arrangements, forming a scaffold …

Spectrin is a large, cytoskeletal, and heterodimeric protein composed of modular structure of α and β subunits, it typically contains 106 contiguous amino acid sequence motifs called …

May 24, 2021 · Spectrin subunits are mainly composed of spectrin repeats, which form a triple-helix supercoil that functions much like a spring to allow spectrin tetramers to expand and …

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of …

Spectrin is an abundant protein in the nervous system, comprising 2.4% of total protein in mammalian brain homogenates. Spectrin is an unusually large protein with a native molecular …

Feb 1, 2014 · βIV-spectrin acts as a multifunctional regulatory platform for sodium channels, and has important roles in maintaining the structure and stability of excitable membranes in heart …

βII spectrin, the most common isoform of non-erythrocyte spectrin, is a cytoskeleton protein present in all nucleated cells. Interestingly, βII spectrin is essential for the development of …

Spectrins are proteins that are responsible for many aspects of cell function and adaptation to changing environments. Primarily the spectrin-based membrane skeleton maintains cell …

This review discusses the spectrin superfamily of proteins that function to connect cytoskeletal elements to each other, the cell membrane, and the nucleus. The signature domain is the …

Jan 25, 2023 · Together with actin, spectrin forms a submembrane cytoskeleton thought to impart mechanical resilience to neuronal processes and mediate signalling events 4.