This blood test checks levels of IGF-1, a growth hormone. Too much or too little can affect bone and tissue growth and development in you or your child.

Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role in childhood growth, and has anabolic effects in adults. [5]

Elevated serum IGF1 and IGFBP3 levels often indicate either a sustained overproduction of GH or excessive rhGH therapy. Endogenous GH excess is caused mostly by GH-secreting pituitary adenomas, resulting in gigantism if acquired before epiphyseal closure …

Measurement of serum IGF-1 has been widely used in the diagnosis of disorders of GH secretion, 2-6 management of disorders that lead to nutritional insufficiency, or catabolism, 7-9 and monitoring both GH and IGF-1 replacement therapy. IGF-1 measurement may also have a role in the physiology of malignant disease. 10,11

There are different reference ranges for normal IGF-1 levels in adults. Also, IGF-1 can be influenced by age, genetics, diet, physical activity, body weight and composition.

Jul 30, 2021 · IGF-1, also known as insulin-like growth factor 1, is a complex and interesting hormone. Is IGF-1 good or bad when it comes to your health? It has the potential to have both effects depending on how much your body produces. Its most important job is to promote cell growth (hence the name).

Nov 9, 2021 · Insulin-like growth factor-1 (IGF-1) is a hormone that, along with growth hormone (GH), helps promote normal bone and tissue growth and development. The test measures the amount of IGF-1 in the blood.

IGF-1 measurement is important for the diagnosis and management of patients with growth hormone (GH) deficiency or acromegaly as well as in their follow-up (1, 2). We previously established normative data for six IGF-I assays using the same large healthy population .

Insulin-like growth factor-1 (IGF-1) in the circulation originates mainly from the liver under control of pituitary growth hormone (GH). Levels of IGF-1 parallel those of GH. IGF-1 levels are therefore indicated in: Diagnosis and treatment monitoring of GH secreting tumours; Investigation of short stature in children

Serum-based immunoassays are typically used to assess IGF-1 levels. Serum is the preferred sample type because concentrations are 100- to 1,000-fold higher than in urine 6; IGF-1 is degraded during renal clearance. 7 Immunoassays, while simple to perform, have a …