In this study we focus on anti-Jo-1 (histidyl-tRNA synthetase). This autoantibody is associated with inflammatory muscle diseases and interstitial lung diseases (ILD). We retrospectively …

Evaluate patients suspected of having polymyositis, dermatomyositis, or polymyositis-scleroderma overlap syndrome. Bernstein RM, Morgan SH, Chapman J, et al. Anti-Jo-1 antibody: A marker …

Apr 24, 2016 · Jo-1 is the most common of a group of autoantibodies called antisynthetase antibodies. We describe the clinical relationship between Jo-1 in a retrospective cohort study …

Jo-1 Antibody - Jo-1 Antibody occurs most frequently (31%) in patients with polymyositis, but has also been found in patients with dermatomyositis, and the polymyositis/scleroderma "overlap …

May 18, 2023 · To reveal the senescence-regulating mechanism of miR-214-5p, we searched for target genes through sequence- and literature-based analysis. Molecular manipulation of miR …

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Anti-Jo-1 autoantibody is the most frequently detected anti-aaRS antibody in ASSD and targets the histidyl tRNA synthetase which catalyses the binding of the histidine to its cognate tRNA …

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May 18, 2023 · Silencing JAG1 or downstream genes of JAG1-Notch signaling, accelerated the senescence of MVECs. Additionally, ectopic overexpression of JAG1 reversed the …

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