The alternative oxidase (AOX) is an enzyme that forms part of the electron transport chain in mitochondria of different organisms. [1][2] Proteins homologous to the mitochondrial oxidase …

Recent work on the trypanosome alternative oxidase has provided a crystal structure of an AOX protein, which contributes to the structure–activity relationship of the inhibitors of AOX.

Recent work on the trypanosome alternative oxidase has provided a crystal structure of an AOX protein, which contributes to the structure−activity relationship of the inhibitors of AOX.

Mar 4, 2024 · Recent work on the trypanosome alternative oxidase has provided a crystal structure of an AOX protein, which contributes to the structure–activity relationship of the …

This involves a two-step biochemical activation of the AOX protein, a covalent modification followed by an allosteric activation, in response to the redox (NADPH) and carbon (pyruvate) …

May 1, 2017 · The alternative oxidase (AOX) protein is present in plants, fungi, protozoa and some invertebrates. It is involved in the mitochondrial respiratory chain, providing an …

Sep 7, 2017 · Alternative oxidase (AOX) is a mitochondrial inner-membrane oxidase that accepts electrons directly from ubiquinol and reduces oxygen to water without involving cytochrome …

Oct 2, 2020 · AOX is a cyanide-resistant, salicylhydroxamic acid-sensitive oxidase that transfers electrons from ubiquinol to oxygen, bypassing the cytochrome chain. AOX has been proposed …

Alternative oxidase (AO) is a highly intriguing protein expressed by lower eukaryotes, such as the invertebrate . This Ciona intestinalis enzyme with the size of <40 kDa has the combined...

oxidase” (AOX). The AOX is an integral protein (32 36 kDa) of the inner mitochondrial membrane. It is encoded by the nuclear genome, is localized on the matrix side of the mitochondrial inner …