Phenacetin (/ fɪˈnæsɪtɪn / ⓘ; acetophenetidin, N- (4-ethoxyphenyl)acetamide[1]) is a pain-relieving and fever-reducing drug, which was widely used following its introduction in 1887. It was withdrawn from medicinal use as dangerous from the 1970s (e.g., withdrawn in Canada in 1973, [2] and by the U.S. Food and Drug Administration in 1983 [3]).

Phenacetin is an odorless fine white crystalline solid with a lightly bitter taste. Used as an analgesic medicine. Phenacetin is a member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen is substituted by a 4-ethoxyphenyl group.

Phenacetin was used as an analgesic and fever-reducing drug in both human and veterinary medicine for many years. It was introduced into therapy in 1887 and was extensively used in analgesic mixtures until it was implicated in kidney disease …

Jun 13, 2005 · Phenacetin was the first NSAID and fever reducer to go on the market. It acts as an analgesic at the spinal cord as well as a negative inotrope at the heart. It can be used to …

Phenacetin, a painkiller, was the world’s first synthetic pharmaceutical drug. It was one of the first painkillers that was not derived from opium while at the same time being absent of anti-inflammatory qualities. Phenacetin was developed in 1878 by an American chemist, Harmon Northrop Morse.

Jan 7, 2025 · Phenacetin was the first NSAID and fever reducer to go on the market. It acts as an analgesic at the spinal cord as well as a negative inotrope at the heart. It can be used to treat subacute rheumatoid arthritis, intercostal neuralgia, and ataxias.

Aug 23, 2023 · Phenacetin is an analgesic and antipyretic drug with distinct pharmacokinetic characteristics. It is absorbed orally and metabolized extensively to paracetamol, which has good bioavailability. Paracetamol undergoes metabolism and is excreted primarily as glucuronide and sulphate conjugates in urine.

Jun 25, 2024 · Phenacetin powder, a compound with a complex and controversial history in the pharmaceutical industry, was once a widely used analgesic and antipyretic medication. Discovered in the late 19th century, phenacetin quickly gained popularity for its effectiveness in relieving pain and reducing fever.

May 28, 2024 · Phenacetin, an organic compound with a fascinating history, has stood as a hallmark in the realm of pain management. Renowned for its effectiveness in alleviating mild to moderate pain and reducing fevers, phenacetin has held a significant role in pharmaceuticals.

Phenacetin, introduced in 1887, was used principally as an analgesic, and was the first fever reducer to go on the market. It is also known historically, to be the very first analgesic without anti-inflammatory properties. Typical doses of 300mg to 500mg a day result in an analgesic effect.