Invitrogen Anti-TAK1 Polyclonal, Catalog # PA1-41100. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF) and Immunohistochemistry (Paraffin) (IHC (P)) applications. …

Mar 25, 2025 · Our mechanistic study revealed that tetrameric PHGDH, through its nonmetabolic function, disrupts the binding of TAK1 to its adaptor protein TAB1, thereby reducing TAK1 …

TGF-β activated kinase 1 (Tak1) encodes a MAP kinase kinase kinase that functions downstream of the products of imd, Fadd and Diap2. It also functions upstream of the IKK complex in the …

Oct 2, 2014 · In this study, we identified TAK1 (encoded by the Map3k7 gene) as a nodal regulator of necroptotic cell death by functioning as a molecular switch in TNFR1 signaling.

Mar 22, 2025 · We show here for the first time that the MAP3K7 (TGF beta activated kinase, TAK1) is responsible for the synergistic costimulation of B cells by BCR and TLR9, resulting in …

Mar 16, 2025 · Here, we demonstrate that the lipotoxicity inducer palmitic acid (PA) significantly increases macrophage PHGDH expression and that PHGDH defi-ciency in macrophages …

Feb 27, 2024 · Lys-63-ubiquitination activates the TGFbeta-activated kinase (Tak1), which feeds back to phosphorylate Imd, triggering the removal of Lys-63 chains and the addition of Lys-48 …

Mar 30, 2025 · Invitrogen Anti-TAK1 Polyclonal, Catalog # PA5-17507. Tested in Western Blot (WB) applications. This antibody reacts with Bovine, Human, Mouse, Non-human primate, Rat …

TAK1 is an upstream MAPK kinase kinase (MAP3K) required for H. pylori-induced MAPK and NF-κB activation, but it remains unclear whether other MAP3Ks are involved in H. pylori-induced …

Mar 25, 2025 · Our mechanistic study revealed that tetrameric PHGDH, through its nonmetabolic function, disrupts the binding of TAK1 to its adaptor protein TAB1, thereby reducing TAK1 …