As soon as a baby requires oxygen, then the 88-93% limits must be applied. Where to place the oxygen saturation probe? The best place is on the right hand/wrist, which will give a pre-ductal reading of oxygen saturation – this is the blood that goes to the brain and eyes.

Oxygen supplementation is an important component of neonatal intensive care for the preterm infant. Ideally, oxygen administration provides adequate oxygenation for the metabolic needs of the neonate while avoiding the consequences of both hypoxemia and hyperoxia.

In view of evidence suggesting adverse outcomes of hyperoxia in both term and preterm neonates, evidence-based recommendations should guide the oxygen therapy. Apart from titration of oxygen therapy, this guideline document also addresses the need of humidification and various technological choices in monitoring and titrating oxygen therapy.

Oxygen concentration should be set to achieve a PaO2 of 50 to 70 mm Hg in preterm infants and 50 to 80 mm Hg in term infants or an oxygen saturation of 90 to 94% in preterm infants and 92 to 96% in term infants.

Dec 1, 2024 · Oxygen is one of the most commonly used drugs in the Neonatal Intensive Care unit (NICU). Oxygen therapy in neonatal care has four goals. Delivery of oxygen to the tissues to avoid anerobic metabolism and lactic acidosis, enabling growth and development, minimizing hypoxic pulmonary vasoconstriction and oxygen toxicity. [ 1 ]

Mar 9, 2023 · The ideal target oxygen range is a compromise among negative outcomes associated with either hyperoxemia (e.g. ROP, BPD) or hypoxemia (e.g. NEC, death). Recent RCTs suggest that a targeted oxygen saturation range of 90% to 95% may be safer than 85% to 89%. Adhering to this narrow target range is challenging but utilizing alarm limits and histogram

Current AAP, AHA and guidelines for neonatal resuscitation (NRP) recommend initial resuscitation with 21% to 30% oxygen. Preterm and term babies who need resuscitation at birth should optimally attain an oxygen saturation value in the interquartile range of pre-ductal saturations measured in healthy term babies following vaginal birth at sea level.

Oxygen can be a life saving therapy for sick and preterm newborns in the intensive care unit. Five large multi center trials aiming to define optimal SpO2 targets in preterm babies have shown that

Oxygen saturations should be targeted within the range of 91-95%, when receiving oxygen therapy, in both preterm and term neonates. Fi0 2 is one of several determinants of arterial oxygenation provided by supplemental oxygen therapy.

We reviewed oxygen physiology and balance, key studies evaluating oxygen saturation targets, and strategies for oxygen use in the neonatal intensive care unit. Oxygen is a potent vasodilator involved in the transition at birth to breathing.