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  1. Necrobiotic Xanthogranuloma - EyeWiki

    Necrobiotic Xanthogranuloma (NXG) is a non-Langerhans cell histiocytosis with multisystem involvement that commonly affects the skin and periorbital structures. There has recently been …

  2. Necrobiotic Xanthogranuloma - American Academy of Ophthalmology

    Mar 1, 2017 · Necrobiotic xanthogranuloma (NXG) is 1 of 4 adult orbital xanthogranulomatous diseases, along with adult-onset asthma with periocular xanthogranuloma, Erdheim-Chester …

  3. Necrobiotic xanthogranuloma | About the Disease | GARD

    Approximately 50% of people with NXG have problems with their eyes, such as burning or itching, blurred vision, double vision, bulging of the eyeball, drooping of the eyelid, and restricted eye …

  4. Necrobiotic xanthogranuloma - UpToDate

    Necrobiotic xanthogranuloma (NXG) is a form of non-Langerhans histiocytosis characterized by the development of red-brown, violaceous, or yellowish cutaneous papules and nodules that …

  5. Necrobiotic xanthogranuloma pathology - DermNet

    Necrobiotic xanthogranuloma is a rare multisystem histiocytic disease usually affecting older adults. The typical clinical lesion is an asymptomatic yellowish indurated plaque in a periorbital …

  6. Systemic therapy of necrobiotic xanthogranuloma: a systematic …

    Necrobiotic xanthogranuloma (NXG) was first described by Kossard and Winkelmann in 1980 and is a rare non-Langerhans cell histiocytosis with no gender preference. The disease mostly …

  7. A Multicenter Cross-Sectional Study and Systematic Review of ...

    Necrobiotic xanthogranuloma (NXG) is a non–Langerhans cell histiocytosis classically associated with paraproteinemia attributable to plasma-cell dyscrasias or lymphoproliferative disorders. …

  8. Orbital necrobiotic xanthogranuloma with necrotizing scleritis and ...

    Aug 7, 2024 · Necrobiotic xanthogranuloma (NXG) is a rare systemic disease, that commonly manifests with orbital and ocular adnexal involvement, presenting with periocular yellow …

  9. Necrobiotic Xanthogranuloma - Mayo Clinic Proceedings

    Necrobiotic xanthogranuloma is a rare disorder, categorized as a cutaneous non-Langerhans cell histiocytosis, often associated with a paraproteinemia, typically of IgG isotype. 1,2 It often …

  10. Necrobiotic xanthogranuloma - visualdx.com

    May 31, 2020 · Necrobiotic xanthogranuloma (NXG) is a rare histiocytic disorder that presents as firm yellow papules and plaques of the skin, most often in the periorbital area. It is strongly …

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