Megavirus [2] is a viral genus, phylogenetically related to Acanthamoeba polyphaga mimivirus (APMV). [3] In colloquial speech, Megavirus chilense is more commonly referred to as just "Megavirus". Until the discovery of pandoraviruses in 2013, it had the largest capsid diameter of all known viruses, as well as the largest and most complex genome ...

Oct 30, 2024 · Megavirus, a member of the nucleocytoplasmic large DNA virus (NCLDV) family, stands as one of the largest and most complex viruses known to science. Its discovery in 2010, following the identification of Mimivirus in 2003, marked a significant milestone in virology and challenged conventional perceptions of viral biology.

Oct 10, 2011 · There are many weird viruses on this planet, but none weirder–in a fundamentally important way–than a group known as the giant viruses. For years, they were hiding in plain sight. They were so...

We recently described Megavirus chilensis, a giant virus isolated off the coast of Chile, also replicating in fresh water acanthamoeba. Its 1,259,197-bp genome encodes 1,120 proteins and is the largest known viral genome. Megavirus and its closest ...

Dec 14, 2011 · The mantle of world's biggest virus has passed from Mimivirus to Megavirus. But in this case, size doesn't matter. It's the genes that these ...

Here, we discuss the known protozoal giant viruses and their potential to infect also humans and animals. Keywords: Protozoa, Giant virus, Virophage. Giant viruses (megaviruses) infecting protozoa (amoebae and flagellates) are microorganisms classified into NCLDVs (Nucleocytoplasmic Large DNA Viruses) [1].

Megavirus is a virus with a single identified species, Megavirus chilensis (MGVC). [1] It is phylogenetically related to or Mimivirus (APMV). [2] MGVC is usually referred to as just “Megavirus”.

Jan 1, 2015 · Megavirus chilensis encodes a predicted copper, zinc superoxide dismutase (Cu,Zn-SOD), an enzyme known to detoxify reactive oxygen species released in the course of host defense reactions.

Here, we present Megavirus chilensis, a giant virus isolated off the coast of Chile, but capable of replicating in fresh water acanthamoeba. Its 1,259,197-bp genome is the largest viral genome fully sequenced so far. It encodes 1,120 putative proteins, of …

Giant viruses mimicking microbes, by the sizes of their particles and the heavily glycosylated fibrils surrounding their capsids, infect Acanthamoeba sp., which are ubiquitous unicellular eukaryotes. The glycans on fibrils are produced by virally encoded enzymes, organized in …