Recent Updates on Bacterial Secondary Metabolites to Overcome Antibiotic Resistance in Gram-Negative Superbugs: Encouragement or Discontinuation? M Jangra, P Kaur, R Tambat, V Raka, N Mahey, N...

Manoj Jangra currently works at Michael G. DeGroote Institute for Infectious Disease (IIDR), McMaster University as a postdoctoral fellow. Manoj does research in isolation, purification and...

Mar 26, 2025 · Gerry Wright, left, and Manoj Jangra are part of the research team that discovered a new class of antibiotics called lariocidin in Hamilton, Ont. (McMaster University) (Georgia Kirkos)

Mar 26, 2025 · Gerry Wright and Manoj Jangra in the lab. Image credit: McMaster University. The discovery is only the first step, however. Now, the team will have to invest a lot of time and energy into finding ...

Mar 26, 2025 · Researcher Gerry Wright, left, and postdoctoral fellow Manoj Jangra, holding a 3D-printed model of lariocidin, the new antibiotic that they discovered together. (Photo by Georgia Kirkos, McMaster University)

Manoj joined the lab in October 2021. He finished his Ph.D from CSIR-Institute of Microbial Technology, India. Manoj is an applied microbiologist with expertise in the isolation and biological evaluation of new antimicrobial compounds from microbes.

Sep 16, 2024 · Here, we report the identification and characterization of the lasso peptide antibiotic, lariocidin (LAR), and its internally cyclized derivative, lariocidin B (LAR-B), produced by Paenabacillussp. M2, with broad-spectrum activity against many bacterial pathogens.

Mar 26, 2025 · Manoj Jangra, a postdoctoral fellow in Wright’s lab, can be reached at [email protected]. For an embargoed copy of the study, please contact Nature directly at [email protected].

In Vitro Evaluation of Antimicrobial Peptide Tridecaptin M in Combination with Other Antibiotics against Multidrug Resistant Acinetobacter baumannii. In-vitro studies on a natural lantibiotic, paenibacillin: A new-generation antibacterial drug candidate to overcome multi-drug resistance.