Jun 28, 2019 · Membrane-type 1 matrix metalloproteinase (MT1-MMP) is a type I transmembrane proteinase that belongs to the matrix metalloproteinase (MMP) family. It is a potent modifier of …

MT1-MMP, also known as MMP-14, is important for the remodeling of the extracellular matrix during various cellular processes, including angiogenesis and wound healing, through its …

MT1-MMP (MMP-14) is a multifunctional protease that regulates ECM degradation, activation of other proteases, and a variety of cellular processes, including migration and viability in …

Membrane-type I matrix metalloproteinase (MT1-MMP), a zinc-dependent endopeptidase, proteolytically cleaves extracellular matrix components, and non-matrix proteins, thereby …

MT1-MMP degrades extracellular matrix to make a path for cells to migrate, sheds cell surface molecules to give migratory signals, and activates ERK (extracellular signal-regulated protein …

Membrane type 1-matrix metalloproteinase (MT1-MMP) functions as a signaling molecules in addition to a transmembrane metalloprotease, which degrades interstitial collagens and …

May 1, 2015 · Among the 6 MT-MMPs, MT1-MMP has the widest substrate specificity, especially against extracellular matrix (ECM) components. Collagens are the most abundant ECM …

Jun 1, 2004 · The activity of membrane-type 1 matrix metalloproteinase (MT1-MMP) is a double-edged sword – it is crucial for both physiological processes and disease progression. MT1 …

Mar 25, 2021 · Here we report that membrane type 1-matrix metalloproteinase (MT1-MMP) co-immunoprecipitates and co-localizes with LDLR and promotes LDLR cleavage. Plasma sLDLR …

Membrane-type matrix metalloproteinase-1 (EC 3.4.24.80, matrix metalloproteinase 14) is an enzyme. [1] . This enzyme catalyses the following chemical reaction. Endopeptidase activity. …