The cells of the GEs are quite homogenous, with the MGE, LGE, and CGE all having small, dark, irregular nuclei and moderately dense cytoplasm, however, each eminence can be identified by the type of progeny that it produces. [6] See the individual GE sections below for more information on the different types of progeny produced.

Nov 4, 2021 · The GE is anatomically subdivided into the medial ganglionic eminence (MGE), the lateral ganglionic eminence (LGE) and the caudal ganglionic eminence (CGE), in which the MGE and LGE develop into...

Apr 22, 2009 · Here we investigated these parameters in the medial ganglionic eminence (MGE) and caudal ganglionic eminence (CGE). The MGE is the anlage for the pallidum (globus pallidus [GP] are related pallidal cell groups), interneurons that tangentially migrate to the pallium (cortex and hippocampus), striatum (Sussel et al. 1999; Marín and Rubenstein ...

Nov 4, 2002 · Through gene expression studies, in vitro migration assays, genetic mutant analysis and in vivo fate mapping in mice, we found that the CGE is a progenitor region that is distinct from both the...

该研究通过单细胞转录组测获得了妊娠期9-18周人脑内侧（mge）、外侧（lge）和尾侧神经节隆起（cge）的单细胞细胞转录组图谱，绘制了不同类型细胞的分化及发育轨迹，挖掘了中间神经元发育过程中关键的调控因子。

In the forebrain, neuronal diversity within the ventral telencephalon is associated with specific transient germinal zones, termed the medial, caudal and lateral ganglionic eminences (MGE, CGE, and LGE, respectively).

The MGE gives preferentially rise to PV + and SOM + INs, whereas the CGE primarily produces 5-HT 3A R + INs. The POA in turn produces a mixed population of GABAergic INs. MGE and CGE-derived INs typically coexpress a combination of different neurochemical markers, some of which are illustrated.

Feb 3, 2010 · By combining an inducible genetic fate mapping strategy with electrophysiological analysis, we have systematically characterized the populations of cortical GABAergic interneurons that originate from the caudal ganglionic eminence (CGE).

Cortical interneuron diversity largely emerges from spatially segregated progenitor cells with distinct transcriptional profiles. The schema shows the main sources of cortical interneurons, CGE, MGE and POA, which contain progenitor cells that can be (more...)

Mar 5, 2018 · Cortical inhibitory neurons are a diverse population that varies widely in morphology, connectivity and patterns of activity 1. This group of neurons is developmentally derived from...