The term "lipid triad" or "atherogenic lipoprotein phenotype" has been introduced to describe a common form of dyslipidemia, characterized by three lipid abnormalities: increased plasma triglyceride levels, decreased HDL-cholesterol concentrations …

Background: Atherogenic dyslipidaemia (AD) and lipid triad (LT) are characterised by high triglyceride levels together with low HDL and normal or high LDL cholesterol and are favoured by a persistent state of insulin resistance (IR), which increases ...

Aug 21, 2020 · Feldman's view of the "lipid triad" suggests that in the context of high-HDL/low-TGs, the larger LDL particle size means LDL has a lower atherogenic potential. However, the predominance of LDL-I and LDL-II (i.e., the largest LDL particles) in individuals with low plasma TGs results in rapid clearance of LDL-C from circulation, and is therefore ...

Aug 9, 2022 · Two relevant forms of lipid abnormalities are atherogenic dyslipidaemia (AD) and lipid triad (LT), which involve alterations in triglyceride levels, HDL-c, and LDL-c. The aim of this study was to assess the linkage of atherogenic AD and …

Apr 27, 2023 · A relationship between atherogenic dyslipidaemia and the three insulin resistance risk scales assessed is revealed, with higher IR mean values and prevalence in people with atherogenic dyslipidaemia and lipid triad. The three scales make it possible to adequately classify the presence of AD and LT. …

The lipid triad refers basically to three lipid abnormalities: increased plasma triglycerides and small dense low density lipoprotein (sd-LDL), and decreased high density lipoprotein cholesterol (HDL-C) concentrations. Since lipid triad is highly atherogenic in nature causing CVD, also called as atherogenic lipoprotein phenotype.

Based on the main alterations in lipid profile, comprising increased TG levels, reduced concentrations of high-density lipoprotein cholesterol (HDL-C), and elevated sdLDL particles, this complex form of dyslipidemia is also recognized as the lipid triad or atherogenic lipoprotein phenotype [45,46].

Even though modification of the atherogenic lipid triad is probably one of the most effective methods of reducing cardiovascular risk, therapy for diabetic dyslipidemia is often directed to first lowering serum LDL-C levels with a HMG-CoA reductase inhibitor.

The lipid triad composed of elevated LDL, low HDL, and high TG levels is traditionally believed to lead to increased development of CVD.

lipid triad. Third, since high triglyceride levels also commonly associate with hypertension, insulin re-sistance (with or without glucose intolerance), and a prothrombotic state, they could be a marker for these nonlipid risk factors. The clustering of …