Jan 31, 2023 · Mechanical Thrombectomy Versus Best Medical Treatment in the Late Time Window in Non-DEFUSE-Non-DAWN Patients: A Multicenter Cohort Study

Feb 8, 2024 · Thrombolytic agents, including tenecteplase, are generally used within 4.5 hours after the onset of stroke symptoms. Information on whether tenecteplase confers benefit beyond 4.5 hours is...

Jan 24, 2018 · Stroke patients in whom thrombectomy can be initiated within 6 to 24 hours should be screened with advanced imaging to determine whether they meet DEFUSE 3 or DAWN criteria for late window thrombectomy. Both late window studies required CT perfusion or DWI to assess the size of the ischemic core and, in DEFUSE 3, CT or magnetic resonance ...

Sep 5, 2023 · The recent MR CLEAN LATE (Endovascular Treatment of Acute Ischemic Stroke in the Netherlands for Late Arrivals) trial showed that patient selection in the 6‐ to 24‐hour window is also possible with single‐phase CT angiography and noncontrast CT.

This study examined the functional outcomes and safety of endovascular treatment (EVT) in acute ischemic stroke (AIS) patients owing to large vessel occlusion of the anterior circulation, presented during a late-time window (6–24 hours after last seen well (LSW)) in a …

May 8, 2019 · Of the entire trial population, 25% of the patients received the assigned intervention in the later time window (>6.0 to 9.0 hours after stroke onset) and 10% in the earlier time window (>4.5...

The collateral-based imaging paradigm using multiphase CTA compares well with CTP in selecting patients for endovascular thrombectomy in the late time window.

Nov 11, 2022 · Objective To assess clinical outcomes of patients with acute ischemic stroke presenting in the late window who underwent mechanical thrombectomy stratified by NCCT admission in comparison with selection by CT perfusion (CTP) …

The Late Window Paradox. Following the publication of the DEFUSE-3 trial, which showed greater clinical benefit of EVT in an extended time window of 6-16 hours after TLSW, many stroke providers became perplexed by the paradoxically better outcomes for …

May 11, 2023 · Recent trials have shown evidence for a benefit from endovascular thrombectomy (EVT) for select patients with stroke who can be treated within the late window, defined as 6 to 24 hours after onset.