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  1. Roles of LAMP-1 and LAMP-2 in lysosome biogenesis and …

    The lysosomal membrane proteins LAMP-1 and LAMP-2 are estimated to contribute to about 50% of all proteins of the lysosome membrane. Surprisingly, mice deficient in either LAMP-1 or …

  2. Revisiting LAMP1 as a marker for degradative autophagy ... - PubMed

    Jul 18, 2020 · LAMP1 (lysosomal associated membrane protein 1) and LAMP2 are distributed among autophagic and endolysosomal organelles. Despite widespread distribution, LAMP1 is …

  3. LAMP2A, LAMP2B and LAMP2C: similar structures, divergent roles

    LAMP2 (lysosomal associated membrane protein 2) is one of the major protein components of the lysosomal membrane. There currently exist three LAMP2 isoforms, LAMP2A, LAMP2B and …

  4. Lysosomal LAMP proteins regulate lysosomal pH by direct …

    Jul 20, 2023 · In this study, we discovered that the ubiquitous lysosome-associated membrane proteins (LAMP-1 and LAMP-2) play an integral role in lysosomal pH homeostasis by …

  5. Lysosome-associated membrane proteins-1 and -2 (LAMP-1 and LAMP-2 ...

    Oct 21, 2016 · Lysosome-associated membrane proteins 1 and 2 (LAMP-1 and LAMP-2) have a large, heavily glycosylated luminal domain composed of two subdomains, and are the most …

  6. LAMP1/2 as potential diagnostic and prognostic marker for brain …

    The Lysosomal associated membrane protein 1 (LAMP1)/2/4 mRNA levels were significantly higher in LGG patients than in healthy controls. Morover, high mRNA expressions of …

  7. The Lysosomal Membrane Protein Lamp2 Alleviates Lysosomal

    Lysosomal membrane-associated protein 2 (Lamp2) is an important component of lysosomal membranes and is involved in both autophagy and LMP. In the present study, we found that …

  8. LAMP1 - Wikipedia

    Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in …

  9. Lysosome-associated membrane proteins-1 and -2 (LAMP-1 and LAMP-2 ...

    Oct 21, 2016 · Lysosome-associated membrane proteins 1 and 2 (LAMP-1 and LAMP-2) have a large, heavily glycosylated luminal domain composed of two subdomains, and are the most …

  10. Normal Lysosomal Morphology and Function in LAMP-1-deficient …

    Lysosomal membranes contain two highly glycosylated proteins, designated LAMP-1 and LAMP-2, as major components. LAMP-1 and LAMP-2 are structurally related. To investigate the …

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