Ke Ruan Fragment-based lead discovery (FBLD) has proven fruitful during the past two decades for a variety of targets, even challenging protein–protein interaction (PPI) systems.

Sep 20, 2023 · Ke Ruan (USTC) discussed the discovery of chemical probes that target membrane-less organelles, found through the use of fragment-based screening of low-molecular-weight drugs.

Ruan, Ke. University of Science of Technology of China. Verified email at ustc.edu.cn. Articles Cited by Public access Co-authors. Title. ... Z Dou, K Ruan, DL Hill, L Li, Y Shi, X Yao. Journal of Biological Chemistry 295 (39), 13419-13431, 2020. 71: 2020: Composite alignment media for the measurement of independent sets of NMR residual dipolar ...

Ke Ruan via Europe PubMed Central BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules Cell Research

Ke Ruan. Professor, School of Life Sciences, University of Science & Technology of China. Tel: 86-551-63607767 Fax: 86-551-63601463 E-mail: [email protected]

We are focused on the Fragment Based Lead Discovery (FBLD) targeting key protein-protein interactions regulating the tumor growth and metastasis. We have accomplished the automated NMR...

Rongsheng Ma#, Qingfeng Li, Aidong Wang, Jiahai Zhang, Zhijun Liu, Jihui Wu, Xuncheng Su*, Ke Ruan*, Determination of pseudocontact shifts of low-populated excited states by NMR chemical exchange...

Ke-He RUAN | Cited by 2,540 | of University of Houston, TX (U of H, UH) | Read 149 publications | Contact Ke-He RUAN

ORCID record for Ke Ruan. ORCID provides an identifier for individuals to use with their name as they engage in research, scholarship, and innovation activities.

Ruan Ke. Address: Room 243, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, 230027, PR China. Tel: 0551-63607767. E-mail: kruan (AT) ustc.edu.cn ....