Dopamine transporter imaging with [(123)I]FP-CIT SPECT ... - PubMed
Background: [(123)I]N-omega-fluoropropyl-2beta-carbomethoxy-3beta-{4-iodophenyl}nortropane ([(123)I]FP-CIT) single photon emission computed tomography (SPECT) is a frequently and routinely used technique to detect or exclude dopaminergic degeneration by imaging the dopamine transporter (DAT) in parkinsonian and demented patients. This technique ...
A New Era of Clinical Dopamine Transporter Imaging Using 123I-FP-CIT
Dec 1, 2012 · In human striatum, 123 I-FP-CIT (A) is taken up more rapidly than 123 I-β-CIT (B). Practical clinical advantage of fast kinetics of 123 I-FP-CIT is that patients can be scanned on same day 3–6 h after injection.
Dopamine transporter imaging with [123I]FP-CIT SPECT ... - Springer
Oct 30, 2007 · [123I]N-ω-fluoropropyl-2β-carbomethoxy-3β-{4-iodophenyl}nortropane ([123I]FP-CIT) single photon emission computed tomography (SPECT) is a frequently and routinely used technique to detect or exclude dopaminergic degeneration by imaging the dopamine transporter (DAT) in parkinsonian and demented patients.
[123I]β-CIT SPECT is a useful method for monitoring dopaminergic ...
Mar 1, 2003 · Objectives: To examine the validity of [123 I]β-CIT SPECT for monitoring the progression of dopaminergic degeneration in Parkinson’s disease; to investigate the influence of short term treatment with D 2 receptor agonists on striatal [123 I]β-CIT binding; and to determine the sample size and frequency of SPECT imaging required to demonstrate a s...
Preclinical evaluation of [18F]FP-CIT, the radiotracer targeting ...
Jul 3, 2024 · We investigated the pharmacokinetic properties of [18 F]FP-CIT and its efficacy for PD diagnosis using murine models. Results: Biodistribution, metabolite and excretion analyses were performed in mice and PD models were induced in rats using 6 …
bei klinisch unklarem Parkinson- oder Tremor-Syndrom frühzeitig im Krankheitsverlauf erfolgen. Unter dem Oberbegrif Parkinson-Syndrom werden Be-wegungsstörungen zusammengefasst, bei denen Akine-sie zusammen mit mindeste.
How useful is [123I]β-CIT SPECT in clinical practice?
Objective: To assess the accuracy and clinical usefulness of [123 I]β-CIT (2β-carbomethoxy-3β- (4-iodophenyl)tropane) SPECT in the differential diagnosis of Parkinson’s disease. Subjects: 185 consecutive patients with symptoms of movement disorder were studied.
DaTSCAN - DocCheck Flexikon
Für die Untersuchung wird ein radioaktives Nuklid (z.B. Jod-123-FP-CIT oder Jod-123-beta-FP-CIT) venös appliziert. Das Nuklid lagert sich anschließend an die präsynaptischen Dopamintransporter im Striatum. Nach einer Wartezeit von 3 bis 4 Stunden wird eine SPECT-Aufnahme des Gehirns angefertigt.
[ (123)I]beta-CIT SPECT is a useful method for ... - ResearchGate
Mar 1, 2003 · To examine the validity of [(123)I]beta-CIT SPECT for monitoring the progression of dopaminergic degeneration in Parkinson's disease; to investigate the influence of short term treatment...
Hirnrezeptorszintigraphie - Nuklearmedizin am Raschplatz …
Die DaTSCAN™-Szintigraphie (auch Hirnrezeptor-Szintigraphie) ist eine nuklearmedizinische Untersuchungsmethode zur Darstellung spezieller Dopamin-Transporter im Gehirn. Mit dieser bildgebenden Untersuchung kann überprüft werden, ob ein Morbus Parkinson oder diesem ähnliche Syndrome vorliegen.