" Heterologous prime-boost immunization is administration of two different vectors or delivery systems expressing the same or overlapping antigenic inserts." [1] "An effective vaccine usually requires more than one time immunization in the form of prime-boost. Traditionally the same vaccines are given multiple times as homologous boosts.

Jan 26, 2022 · Homologous and heterologous booster vaccines had an acceptable safety profile and were immunogenic in adults who had completed a primary Covid-19 vaccine regimen at least 12 weeks earlier.

Jun 21, 2022 · Demonstrating with the AstraZeneca base vaccine supplemented by an mRNA vaccine booster, the authors concluded that “the heterologous boost immunisation strategy provides an immune response...

Dec 22, 2022 · Subunit, recombinant, polysaccharide, and conjugate vaccines use specific pieces of the germ—like its protein, sugar, or capsid (a casing around the germ). Because these vaccines use only specific pieces of the germ, they give a very strong immune response that’s targeted to key parts of the germ.

Jun 25, 2021 · In conclusion, heterologous vaccination regimens against COVID-19 provide an opportunity to speed up vaccination campaigns worldwide, maximising their impact on the control of the pandemic. This study is the first report of a randomised controlled trial testing heterologous vaccination, and should be the basis for future studies.

Jul 10, 2021 · In conclusion, heterologous vaccination regimens against COVID-19 provide an opportunity to speed up vaccination campaigns worldwide, maximising their impact on the control of the pandemic. This study is the first report of a randomised controlled trial testing heterologous vaccination, and should be the basis for future studies.

Jul 14, 2021 · Because of concerns about thrombotic events after vaccination with ChAdOx1 nCoV-19 (Oxford–AstraZeneca), 1 several European countries have recommended heterologous messenger RNA (mRNA) boost...

Heterologous immunity can broaden the protective outcomes of vaccinations, and natural resistance to infections. Besides exogenous microbes/pathogens and/or vaccines, endogenous microbiota can also impact the outcomes of an infection and/or …

To sustain and prolong the duration of protection, a third dose of inactivated vaccine or a heterologous vaccine could be necessary. This study explores the utility of homologous and heterologous prime-boost strategies to improve the protective immune responses against SARS-CoV-2 in a mouse model.

Mar 31, 2022 · All eligible persons should receive recommended COVID-19 booster doses to prevent moderate to severe COVID-19. Adult Janssen primary vaccine recipients should preferentially receive a heterologous mRNA vaccine booster dose ≥2 months later.