We found an increased synchronization between the vHPC and mPFC and identified specific mPFC neural subpopulations that selectively respond to object–context associations, and their …

Nov 17, 2021 · This study revealed that the HPC and mPFC theta oscillations and their temporal coupling is correlated with recognition memory-guided behavior. During novel object …

Sep 2, 2024 · Here, we showed that neuronal activity in the dHP affects stress-coping behaviors in mice via excitatory projections to the medial prefrontal cortex (mPFC). The antidepressant …

Specifically in the HPC-mPFC, alterations in proteins related to AD, such as the decay of calcium-independent phospholipase A2 (iPLA2) and the increase of amyloid-β peptide (Aβ), decreased …

The hippocampal formation (HPC) and medial prefrontal cortex (mPFC) have well-established roles in memory encoding and retrieval. However, the mechanisms underlying interactions …

Feb 24, 2021 · Here we show that novelty resets the neural circuits that link the ventral hippocampus (vHPC) and the mPFC, facilitating the ability to overcome an established strategy.

A striking finding in the current study is that, in the object-in-place arms, inactivating the mPFC in the HP-CTRL group resulted in almost identical effects on performance (i.e., chance level) …

Here, we showed that neuronal activity in the dHP affects stress-coping behaviors in mice via excitatory projections to the medial prefrontal cortex (mPFC). The antidepressant ketamine …

Nov 1, 2022 · In this review, we summarize current knowledge on the hippocampal-medial prefrontal cortex (HPC-mPFC) circuit in normal brain function with a focus on oscillations and …

Sep 15, 2019 · In this study we aimed to characterise changes in neuroinflammation in the medial prefrontal cortex (mPFC) and hippocampus (HP) in a rat model of neuropathic pain (NP) and …