Jan 7, 2021 · NPPN can increase the thymus index, cellular immunity, humoral immunity, and bone marrow hematopoietic function of immunosuppressive and bone marrow-suppressed mice induced by the chemotherapy drug CTX. NPPN were used to treat H22 tumor-bearing mice.

H22 tumor-bearing mice were used to investigate the effects of the combination treatment with GFG and CTX on anti-tumor effects and reducing side effects of CTX in our experiment. The results showed that CTX alone could effectively inhibit H22 tumor growth compared with the Mod group (p < 0.01, Figure 1A,B). However, mice in the CTX group began ...

The results showed that Pteris multifida Poir total flavonoids have some inhibitory effect on growth of H22 tumour in mice. The tumour inhibition rate of high dose was 49.36%, and low dose was 33.97%. Although its anti-tumour effect was not stronger than CTX, it can enhance spleen and thymus indices and improve immune function of mice.

Oct 24, 2019 · These results suggested that the treatment with CTX and 300 mg/kg RA could effectively inhibit the tumor growth in the mice-bearing H22 tumors. Furthermore, CTX could inhibit the thymus and spleen indexes of tumor-bearing mice compared with model group (p < 0.05), whereas RA treatment had little effect on the immune indexes ( Table 3 ...

Dec 2, 2021 · The polysaccharide in-vivo against H22 malignant ascites tumor cells shows an evident increase in cytokines and decrease in pro-survival proteins in tumor cells that eventually leads to the increasing in the survival period in mice.

Jan 7, 2021 · To evaluate the effects of NPPN on the immune function and hematopoietic function of Kunming mice, NPPN has been combined with CTX and applied to H22 tumor-bearing mice. Though CTX slowed down tumor growth, it resulted in sever immunosuppressive and myelosuppression in mice.

Objective: To investigate the effect of Ganoderma Lucidum Spore Oil (GLSO) on the tumor growth and survival of H22 tumor-bearing mice treated with cyclophosphamide (CTX), and explore the underlying mechanism.

SNP inhibited the growth of tumor in H22-bearing mice and protected the immune organ. The mechanism underlying the inhibition of tumor might be related to the upregulation of caspase-3 and downregulation of bcl-2.

As shown in Figure 2 A,B, the thymus index of mice treated with high doses of GFG combined with CTX was significantly lower than that of the Mod group and significantly higher than that of the...

PCS has a potent inhibitory effect on the growth of implanted H22 tumors in mice and has a synergetic effect and an attenuated toxic effect in combination with CTX.