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  1. Globus pallidus - Wikipedia

    In primates, the globus pallidus is divided into two parts by a thin medial medullary lamina. [7] . These are the internal globus pallidus (GPi) and the external globus pallidus (GPe); both are composed of closed nuclei surrounded by myelinic walls. [citation needed]

  2. Neuroanatomy, Globus Pallidus - StatPearls - NCBI Bookshelf

    Feb 20, 2023 · The medial medullary lamina of the white matter divides the GP into globus pallidus internus (GPi) and globus pallidus externus (GPe). The GPi is the medial subdivision, whereas GPe is the lateral subdivision.

  3. Globus Pallidus Internus (GPi) Deep Brain Stimulation for …

    We review the history of the globus pallidus internus (GPi) as target for deep brain stimulation (DBS), which is now an established, safe and effective method of treating the motor complications of advanced Parkinson’s disease (PD).

  4. Functional connectivity and integrative properties of globus …

    The globus pallidus consists of the external (GPe) and the internal (GPi) segments. The GPe and GPi have different functional roles. The GPe is located centrally within multiple basal ganglia feedforward and feedback connections. The GPi is an ...

  5. Internal globus pallidus - Wikipedia

    The internal globus pallidus (GPi or medial globus pallidus) is one of the two subcortical nuclei that provides inhibitory output in the basal ganglia, the other being the substantia nigra pars reticulata.

  6. Connectivity and Functionality of the Globus Pallidus Externa …

    In this review, we will summarize the main findings on the composition, connectivity and functionality of different GPe cell populations and the potential GPe-related mechanisms of PD symptoms to better understand the cell type and circuit …

  7. Neuroanatomy, Globus Pallidus - PubMed

    Feb 20, 2023 · The major output of the striatum is through the GPe. The GPi acts as the final output for both direct and indirect pathways of the basal ganglia network. The thalamus, however, is slightly different.

  8. Organization of the Globus Pallidus - ScienceDirect

    Jan 1, 2016 · This chapter describes the anatomical and physiological organization of the external and internal segments of the globus pallidus (GPe and GPi, respectively).

  9. Cell and circuit complexity of the external globus pallidus

    Jun 19, 2023 · In the simplified basal ganglia circuit, the cortex provides excitatory inputs to both the dorsal striatum (dStr) and the subthalamic nucleus (STN). They in turn project to the substantia nigra...

  10. Functional connectivity and integrative properties of globus …

    Dec 15, 2011 · In rodents and carnivores, the GPi is encapsulated in the internal capsule, hence it is also called the entopeduncular nucleus. Though the GPe and GPi receive similar inputs, GPe and GPi project to different sites and thus have different functional roles in basal ganglia information processing.

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