CSNK1A1 Gene - GeneCards | KC1A Protein | KC1A Antibody
Mar 28, 2025 · CSNK1A1 (Casein Kinase 1 Alpha 1) is a Protein Coding gene. Diseases associated with CSNK1A1 include Enterobiasis and Amelogenesis Imperfecta, Type Iiia. …
Casein kinase 1, alpha 1 - Wikipedia
Casein kinase I isoform alpha is an enzyme that in humans is encoded by the CSNK1A1 gene. [5]
Casein kinase 1α: biological mechanisms and theranostic potential ...
May 24, 2018 · Casein kinase 1α (CK1α) (encoded by CSNK1A1 in humans) is a member of the CK1 family of proteins that has broad serine/threonine protein kinase activity [1, 2, 3, 4] (Fig. …
CSNK1A1/CK1α suppresses autoimmunity by restraining the …
Taken together, our study reveals a novel regulatory role of CSNK1A1 in the autophagic degradation of STING1 to maintain immune homeostasis. Manipulating CSNK1A1 through …
CSNK1A1 casein kinase 1 alpha 1 [ (human)] - National Center for ...
CSNK1A1/CK1alpha suppresses autoimmunity by restraining the CGAS-STING1 signaling. Selective CK1alpha degraders exert antiproliferative activity against a broad range of human …
CSNK1A1 casein kinase 1 alpha 1 [ Homo sapiens (human) ]
Feb 8, 2025 · Enables protein serine/threonine kinase activity. Involved in several processes, including peptidyl-serine phosphorylation; positive regulation of proteasomal ubiquitin …
Role of casein kinase 1A1 in the biology and targeted therapy of …
The Casein kinase 1A1 gene (CSNK1A1) is a putative tumor suppressor gene located in the common deleted region for del(5q) myelodysplastic syndrome (MDS). We generated a murine …
Abstract 3588: Discovery of potent and selective CSNK1A1 …
Jun 15, 2022 · In an academic-industry collaboration, we a) developed first-in-class potent and selective ATP-competitive CSNK1A1 small molecule inhibitors with preclinical anti-cancer …
Csnk1a1 casein kinase 1, alpha 1 [ (house mouse)] - National …
Feb 18, 2025 · Enables protein serine/threonine kinase activity. Involved in negative regulation of NLRP3 inflammasome complex assembly and protein phosphorylation. Acts upstream of or …
Csnk1a1 inhibition modulates the inflammatory secretome and …
Casein kinase 1 alpha 1 (CK1α) (encoded on chromosome 5q by Csnk1a1) is considered an attractive target for Tp53 wild‐type acute myeloid leukaemia (AML) treatment. In this study, we …