Collagen-producing lung cell atlas identifies multiple subsets with ...
Apr 21, 2020 · Collagen-producing cells maintain the complex architecture of the lung and drive pathologic scarring in pulmonary fibrosis. Here we perform single-cell RNA-sequencing to …
Alveolar fibroblast lineage orchestrates lung inflammation and …
Jul 10, 2024 · Using whole-lung imaging, we found tdTomato + signals distributed diffusely throughout the alveolar region, whereas Col–GFP signals prominently highlighted …
一篇NC文献部分复现——小鼠正常肺和纤维化肺细胞的 scRNA …
Nov 24, 2023 · 胶原生成细胞 （Collagen-producing cells）维持肺的复杂结构并驱动肺纤维化的病理性瘢痕形成。 文章中进行scRNA-seq，以鉴定正常和纤维化肺中所有胶原生成细胞，在小 …
013134 - 2.3ColGFP Strain Details - The Jackson Laboratory
013134 B6.Cg-Tg (Col1a1*2.3-GFP)1Rowe/J This transgenic 2.3ColGFP mutant mouse strain expresses Green Fluorescent Protein in osteoblasts and osteocytes and may be useful in …
Visualization of specific collagen-producing cells by Col1-GFP
Oct 20, 2018 · Because of its highly specific and physiologically accurate expression, our new Tg mouse line will help to accurately elucidate not only type I collagen-producing cells in normal …
Col1a1-GFP transgene expression in developing incisors
Our analysis of these GFP-expressing transgenic mice shows that the 2.3-kb promoter fragment directs strong expression of GFP only to bones and teeth, whereas the 3.6-kb fragment of …
Adult-specific collagen COL-19 is dispensable for contact …
In this study, we investigate the potential modulatory role of adult-specific collagen COL-19 in contact-mediated mate recognition. Our study shows that the expression of COL-19 ::GFP is …
Generation of Col-GFP carrying immortalized cells. (A) Analysis of …
Col-GFP are a non-commercial murine HSC cell line that expresses GFP under the control of the Col1 promoter/enhancer and it is shown to be a suitable tool for investigating profibrogenic …
Fibrocytes Are Not an Essential Source of Type I Collagen During …
Nov 11, 2014 · Progressive fibrosis involves accumulation of activated collagen producing mesenchymal cells. Fibrocytes are hematopoietic-derived cells with mesenchymal features …
Visualization of specific collagen-producing cells by Col1-GFP ...
Oct 20, 2018 · To exclude the possibility of non-specific EGFP expression in the existing Tg mouse line and specifically monitor type I collagen-producing cells, we generated a new Tg …