Chronic myelomonocytic leukemia (CMML) is a type of cancer that starts in blood-forming cells of the bone marrow and invades the blood. It affects mainly older adults. About Chronic Myelomonocytic Leukemia

Chronic myelomonocytic leukemia (CMML) is cancer of the blood. CMML is considered to be one of the myeloproliferative neoplasms (MPNs), a type of chronic blood cancer in which a person's bone marrow does not make blood effectively.

Mar 17, 2025 · Chronic myelomonocytic leukemia (CMML) is a blood cancer that causes high levels of abnormal white blood cells called monocytes. It can cause fatigue and reduce your number of healthy blood cells. In about 20% of cases, it progresses to acute myeloid leukemia.

CMML-1: Blasts make up less than 5% of white blood cells in the blood and less than 10% of the cells in the bone marrow. CMML-2: Blasts make up 5% to 19% of white blood cells in the blood, or they make up 10% to 19% of the cells in the bone marrow.

Most people diagnosed with chronic myelomonocytic leukemia (CMML) have one of three different subtypes of CMML. Doctors classify CMML subtypes by the percentage of blast cells ("blasts") in the blood and bone marrow.

Chronic myelomonocytic leukemia (CMML) is a type of leukemia, which are cancers of the blood-forming cells of the bone marrow. In adults, blood cells are formed in the bone marrow, by a process that is known as haematopoiesis.

CMML -1 means you have less than 5 % blast cells in your blood or less than 10 % blasts in your bone marrow. CMML - 2 means you have 5 -19% blast cells in your blood and 10-19% in your bone marrow. Knowing your type of CMML, along with other factors, helps your doctor to decide on your risk group.

May 23, 2024 · There are two types of CMML. Type 1 has less than 5% blasts (immature blood cells) and type 2 has between 5-20% blasts in the blood (normal blood has less than 1%). Knowing the specific type of CMML helps doctors to determine the best treatment options.

Jul 13, 2017 · Chronic myelomonocytic leukemia (CMML), a clonal hematopoietic malignancy characterized by persistent monocytosis, combines myeloid cell proliferation with myeloid cell dysplasia and ineffective hematopoiesis, and has thus been classified by the World Health Organization (WHO) as a myelodysplastic syndrome (MDS)/myeloproliferative neoplasm (MPN ...

Disease overview: Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder with overlapping features of myelodysplastic syndromes and myeloproliferative neoplasms, characterized by prominent monocytosis and an inherent risk for leukemic transformation (~15%-20% over 3-5 years).