Clozapine is available only from a certified pharmacy under a special program. Warnings. Clozapine affects your immune system. You may get infections more easily, even serious or …

Use clozapine cautiously in patients with cardiovascular or cerebrovascular disease or conditions predisposing to hypotension (eg, dehydration, use of antihypertensive medications).Seizures. …

Mar 11, 2025 · Concomitant use of clozapine is not recommended, however, if a strong CYP450 3A4 inducer is necessary, a dose increase of clozapine dose may be needed. Monitor for …

Nov 19, 2024 · Clozapine can cause severe neutropenia (ANC <500/mm 3), which may lead to serious and potentially fatal infections. Patients initiating or continuing treatment with clozapine …

Apr 6, 2025 · Clozapine is almost completely metabolized prior to excretion, and only trace amounts of unchanged drug are detected in the urine and feces. Clozapine is a substrate for …

Jan 1, 2025 · Clozapine can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, …

Taking this medicine (clozapine tablets) in the third trimester of pregnancy may lead to uncontrolled muscle movements and withdrawal in the newborn. How is this medicine …

Mar 25, 2025 · For abrupt clozapine discontinuation for a reason unrelated to neutropenia, continuation of the existing ANC monitoring is recommended for general population patients …

Clozapine affects your immune system and can have long lasting effects on your body. You may get infections more easily, even serious or fatal infections. You may need frequent medical …

Taking clozapine oral suspension in the third trimester of pregnancy may lead to uncontrolled muscle movements and withdrawal in the newborn. How is this medicine (Clozapine Oral …