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  1. Catenin - Wikipedia

    Most studies investigating catenin actions have focused on α-catenin and β-catenin. β-catenin is particularly interesting as it plays a dual role in the cell. First of all, by binding to cadherin …

  2. Wnt/β-catenin signalling: function, biological mechanisms, and ...

    Jan 3, 2022 · The Wnt/β-catenin pathway comprises a family of proteins that play critical roles in embryonic development and adult tissue homeostasis.

  3. The many faces and functions of β-catenin - PMC - PubMed …

    β-Catenin (Armadillo in Drosophila) is a multitasking and evolutionary conserved molecule that in metazoans exerts a crucial role in a multitude of developmental and homeostatic processes. …

  4. The catenin family at a glance - PMC - PubMed Central (PMC)

    Members of the catenin family were first isolated complexed with the cytoplasmic domains of cadherins at cell-cell junctions, and this relationship is considered one of the defining aspects …

  5. Catenin beta-1 - Wikipedia

    Catenin beta-1, also known as β-catenin (beta-catenin), is a protein that in humans is encoded by the CTNNB1 gene. β-Catenin is a dual function protein , involved in regulation and …

  6. Wnt/β-catenin signaling: components, mechanisms, and diseases

    Signaling by the Wnt family of secreted glycolipoproteins via the transcription co-activator β-catenin controls embryonic development and adult homeostasis. Here we review recent …

  7. Pathology Outlines - Beta catenin

    CT and ultrasound imaging of the abdomen exhibited a solid and cystic tumor measuring 8 cm near the tail of the pancreas. Tumor cells were positive for beta catenin, CD10, CD56, CD117 …

  8. Catenin - an overview | ScienceDirect Topics

    Catenin is a protein that plays a dual role in intercellular adhesion and transcriptional regulation. It facilitates the binding of cadherins to the actin cytoskeleton and activates target genes of the …

  9. Mechanistic insights into Wnt–β-catenin pathway activation and …

    Jan 24, 2025 · Although a simple model describing Wnt–β-catenin signalling is widely used to introduce this pathway and has largely remained unchanged over the past 30 years, in this …

  10. Mechanistic insights into Wnt-β-catenin pathway activation

    Jan 24, 2025 · Defects in canonical Wnt signalling, which is transduced intracellularly by β-catenin, have been associated with developmental disorders, degenerative diseases and …

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