
CCR6 as a mediator of immunity in the lung and gut - PMC
CCR6 is an important receptor that is involved in regulating several aspects of mucosal immunity, including the ability to mediate the recruitment of immature dendritic cells (DCs) and mature …
C-C chemokine receptor type 6 - Wikipedia
Chemokine receptor 6 also known as CCR6 is a CC chemokine receptor protein which in humans is encoded by the CCR6 gene. [5] CCR6 has also recently been designated CD196 (cluster of …
CCR2 and CCR6, but Not Endothelial Selectins, Mediate the …
Early DC recruitment depends in part on CCR2 to traverse vascular endothelium, plus CCR6 to traverse alveolar epithelium. The recruitment of circulating immature DC represents a potential …
CCR6-Mediated Dendritic Cell Activation of Pathogen ... - Cell …
Here, we demonstrate that a specialized DC subset in Peyer's patches (PPs) mediates the rapid activation of pathogen specific T cells. This DC subset is characterized by the expression of …
The Role of CC Chemokine Receptor 6 in Host Defense in a Model …
In this article, we provide data that link CCR6-mediated DC influx into the lung as a necessary component of host defense in neutropenic mice with invasive aspergillosis. Several studies …
CCR6 is an important receptor that is involved in regulating several aspects of mucosal immunity, including the ability to mediate the recruitment of immature dendritic cells (DCs) and mature …
These three cell types have specialized func-tion; the myeloid type (CD11b+CD8a2CCR6+) activates primarily T helper (Th)-2 T cells that produce IL-10, the CD11b2CD8a+CCR62 DCs …
The CC chemokine CCL20 and its receptor CCR6 - PubMed
CCL20, alternatively named liver and activation-regulated chemokine (LARC), macrophage inflammatory protein-3alpha (MIP-3alpha) or Exodus-1, is the only chemokine known to …
Recruitment of circulat-ing DC precursors, including Gr1+monocytes, pre-cedes the sequential accumulation of CD11c+ MHC class II+DCs in dermis and epithelium via a CCR6/ CCL20 …
CCR6 expression defines regulatory effector/memory-like cells …
Apr 1, 2005 · In this study we show that the chemokine receptor CCR6 is expressed on a distinct subset of mouse Treg cells. Similar to their CD25 - counterparts, CCR6 + Treg cells exhibit …