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  1. CCR6 as a mediator of immunity in the lung and gut - PMC

    CCR6 is an important receptor that is involved in regulating several aspects of mucosal immunity, including the ability to mediate the recruitment of immature dendritic cells (DCs) and mature …

  2. C-C chemokine receptor type 6 - Wikipedia

    Chemokine receptor 6 also known as CCR6 is a CC chemokine receptor protein which in humans is encoded by the CCR6 gene. [5] CCR6 has also recently been designated CD196 (cluster of …

  3. CCR2 and CCR6, but Not Endothelial Selectins, Mediate the …

    Early DC recruitment depends in part on CCR2 to traverse vascular endothelium, plus CCR6 to traverse alveolar epithelium. The recruitment of circulating immature DC represents a potential …

  4. CCR6-Mediated Dendritic Cell Activation of Pathogen ... - Cell …

    Here, we demonstrate that a specialized DC subset in Peyer's patches (PPs) mediates the rapid activation of pathogen specific T cells. This DC subset is characterized by the expression of …

  5. The Role of CC Chemokine Receptor 6 in Host Defense in a Model …

    In this article, we provide data that link CCR6-mediated DC influx into the lung as a necessary component of host defense in neutropenic mice with invasive aspergillosis. Several studies …

  6. CCR6 is an important receptor that is involved in regulating several aspects of mucosal immunity, including the ability to mediate the recruitment of immature dendritic cells (DCs) and mature …

  7. These three cell types have specialized func-tion; the myeloid type (CD11b+CD8a2CCR6+) activates primarily T helper (Th)-2 T cells that produce IL-10, the CD11b2CD8a+CCR62 DCs …

  8. The CC chemokine CCL20 and its receptor CCR6 - PubMed

    CCL20, alternatively named liver and activation-regulated chemokine (LARC), macrophage inflammatory protein-3alpha (MIP-3alpha) or Exodus-1, is the only chemokine known to …

  9. Recruitment of circulat-ing DC precursors, including Gr1+monocytes, pre-cedes the sequential accumulation of CD11c+ MHC class II+DCs in dermis and epithelium via a CCR6/ CCL20 …

  10. CCR6 expression defines regulatory effector/memory-like cells …

    Apr 1, 2005 · In this study we show that the chemokine receptor CCR6 is expressed on a distinct subset of mouse Treg cells. Similar to their CD25 - counterparts, CCR6 + Treg cells exhibit …

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