Overall, the brain stimulation reward and IV drug self-administration studies demonstrate that the effects of morphine are qualitatively different between genotypes and suggest that morphine has greater addiction liability in the C57 mouse.

This study examined individual differences in male and female C57BL/6J (C57) mice responding for intravenous cocaine reinforcement. The experiment used 4 groups of mice, distinguished by sex and cocaine unit dose (0.3 or 1 mg/kg/infusion).

Astragaloside IV can activate PPARγ signaling in intestinal epithelial cells and reduces DNA damage caused by intestinal inflammation, thereby inhibiting colon tumourigenesis. The novelty of this study is to use PPARγ as the target to inhibit DNA damage to prevent the occurrence of CAC.

尾静脉注射（Intravenous Injections，IV） 小鼠尾部背侧及两侧各有一根静脉，由于两侧的静脉易于固定，可用于注射及采血。 （1）将小鼠用专门的保定器保定，使其尾部充分暴露。 （2）将其尾部用酒精棉球反复擦拭，并轻轻捏住尾根部，轻弹注射位置，以使血管充盈扩张，或用45-50℃的温水浸泡30秒。 （3）用拇指和食指固定住尾部。...

Astragaloside IV (AST-IV) is a principal component of Radix Astragali seu Hedysari (Huangqi) and exerts potential neuroprotection in experimental ischemic stroke. Here, we systematically assessed the effectiveness and possible mechanisms of AST-IV …

Mar 20, 2008 · Key aspects of the protocol are the need to use chicken collagen for immunization and the importance of avoiding aggressive behavior in males. The incidence of arthritis varies from 50 to 80% and...

C57 mice presented a worse outcome than BALB/c mice after infection with O157:H7 bacteria, leading to severe intestinal damage and epithelial barrier dysfunction, together with significant Stx-dependent renal damage and death in an increased percentage of mice.

Jan 31, 2009 · In the present study, we tested an immortalized syngeneic endothelial cell line originated from C57BL mice as a vaccine for treatment of melanoma.

Dec 26, 2017 · Apart from their Th1-/Th2-polarization, C57 BL/6 and Balb/c mice are also known to differ with regard to their NK cell capabilities: C57 BL/6 NK cells produce higher cytotoxicity against xenogeneic Chinese hamster ovary (CHO) cells than Balb/c mice.

My advice to you, inject into retroorbital venous sinus. This is very much easier. Correct writing of mouse strain name is C57BL/6. Once you've warmed the mice, make sure you have a really good...