Boronic acids act as Lewis acids. Their unique feature is that they are capable of forming reversible covalent complexes with sugars, amino acids, hydroxamic acids, etc. (molecules with vicinal, (1,2) or occasionally (1,3) substituted Lewis base donors (alcohol, amine, carboxylate)).

Aug 23, 2019 · If the ammonium group perturbs the pK a s of the boronic acids and boronate esters, it is logical that it could also play a key role in the mechanism of boronate ester formation.

A base-free, nickel-catalyzed decarbonylative coupling of carboxylic acid fluorides with diboron reagents selectively affords aryl boronate esters. The method is applicable to various (hetero)aryl carboxylic acid fluorides as well as diverse diboron reagents.

Dec 30, 2021 · Boronates are esters and salts of boronic acid. Boronic acid is a compound related to boric acid in which one of the three hydroxyl groups has been replaced by either an alkyl or an aryl group. The boronic acids are derived from boron, an element found in the earth’s crust as boric oxide (B (OH)O).

The boronate oxidation takes advantage of hydrogen peroxide’s specific molecular characteristics, particularly its enhanced nucleophilicity due to the α-effect (Jencks & Carriulo, 1960; Ren & Yamataka, 2007), imparted by adjacent nonbonding orbitals on its oxygen atoms, and the weak O …

Oct 5, 2014 · The synthesis of three boronate esters obtained by reacting 4-fluorophenylboronic (1), 4-iodophenylboronic (2) and 3,4-chlorophenylboronic (3) acids with 2,4,5-trihidroxybenzaldehyde is reported. The structural characterization was determined by spectroscopic and spectrometric techniques.

A wide range of synthetically useful boronate esters are readily obtained demonstrating broad utility and functional group tolerance. The catalyst can be reused for up to six runs without appreciable loss in activity.

Aug 29, 2017 · Boronate affinity monolithic capillary is an advanced functional material which has appeared in recent years, which allows for facile capture/release of glycoproteins in a pH-switchable fashion.

Dec 5, 2007 · Boronate | BO2-2 | CID 21867279 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

In this review, several activities of boronic acids, such as anticancer, antibacterial, antiviral activity, and even their application as sensors and delivery systems are addressed. The synthetic processes used to obtain these active compounds are also referred.