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  1. Know Your Osteoporosis Blood Test Markers - WebMD

    Bone-specific alkaline phosphatase (Bone ALP or BALP). This is an estimate of the rate of bone formation over your entire skeleton.

  2. Bone alkaline phosphatase: An important biomarker in chronic kidney ...

    Feb 1, 2020 · Bone alkaline phosphatase (BALP) is essential for biomineralization. Recent findings demonstrate a crucial role for BALP in the pathogenesis of vascular calcification and identified it as a promising predictor of mortality in CKD.

  3. The Novel Bone Alkaline Phosphatase Isoform B1x Is Associated …

    Circulating alkaline phosphatase (ALP) is an independent cardiovascular risk marker. Serum bone ALP (BALP) isoforms indicate bone turnover and comprise approximately 50% of total circulating ALP. In chronic kidney disease (CKD), mortality is highest ...

  4. Alkaline Phosphatase Bone Isoenzyme - ScienceDirect Topics

    This type of ALP is functionally similar but antigenically different from hepatic and placental ALP. 27 In the absence of liver failure, total ALP could be an indicator of osteoblastic activity, but the bone ALP isoenzyme (bALP) is preferable because of higher specificity. 28 The concentration of bALP reflects osteoblastic activity. 29

  5. Biomarkers as therapy monitoring for postmenopausal …

    May 18, 2021 · Our findings suggest that bALP and NTx may represent useful, valid, and reliable tools for therapy monitoring for postmenopausal osteoporotic patients. Higher bALP and NTx were associated to lower femoral BMD and higher rate of non-vertebral fractures, respectively.

  6. The Levels of Bone Alkaline Phosphatase (BALP) and Soluble …

    The aim of this study was to assess the usefulness of bone-specific alkaline phosphatase (BALP) and the extracelluar domain of human epidermal growth factor receptor 2 (ECD/HER-2) measurements in pediatric patients with osteosarcoma as prospective ...

  7. Clinical usefulness of bone alkaline phosphatase in osteoporosis

    We have evaluated two commercial assays for serum bone specific alkaline phosphatase (bALP) as a marker of bone turnover in a group of 35 postmenopausal women with osteoporosis during their first year of treatment with the anti-resorptive drug, alendronate.

  8. Total and bone-specific alkaline phosphatase are associated

    Background: Alkaline phosphatase (ALP) and bone-specific ALP (BALP) are implicated in the abnormal skeletal mineralization and accelerated vascular calcification in chronic kidney disease (CKD) patients. Whereas ALP and BALP may predict mortality in CKD, BALP is reported to have higher sensitivity and specificity than total ALP in reflecting ...

  9. Bone-Specific Alkaline Phosphatase (BALP) - empendium

    May 9, 2022 · Bone-specific alkaline phosphatase (BALP) [S/P] Reference range, target level, or decision threshold <150 IU/L!!! Interpretation of results. ↑ Bone diseases (bone formation): Osteomalacia (primary hyperparathyroidism, CKD, vitamin D deficiency, metastases), Paget disease, osteoporosis

  10. Activity or mass concentration of bone-specific alkaline

    Background: Recently published data identified bone-specific alkaline phosphatase (BALP) as a good marker of bone formation in different bone diseases and osteoporosis. Two methods are available for BALP determination: one measures enzyme …

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