Although this strain is refractory to many tumors, it is a permissive background for maximal expression of most mutations. C57BL/6J mice are resistant to audiogenic seizures, have a …

C57BL/6, often referred to as "C57 black 6", "B6", "C57" or "black 6", is a common inbred strain of laboratory mouse. It is the most widely used "genetic background" for genetically modified …

The C57BL/6 mouse is a multipurpose model that can be used for research into physiology, immunology, safety and efficacy, oncology and genetics, as well as mouse model creation. B6 …

Jan 3, 2019 · C57BL/6J mice are resistant to audiogenic seizures, have a relatively low bone density, and develop age related hearing loss. They are also susceptible to diet-induced …

Mar 30, 2020 · In C57BL/6 mice, Th1 immune response and IFNγ production play the key role. Alternately, it is easier to induce Th2 immune response in BALB/c mice, which is very common …

The C57BL/6 (B6) mouse strain is the most widely used strain in biomedical research, with nearly 25,000 articles on Pubmed documenting its use. Nearly half of these articles cite the use of …

Oct 2, 2017 · Understanding the B6 mouse, its origins, characteristics and potential is required to make full and appropriate use of this model in research and drug discovery. The B6 mouse is …

The Black 6 (B6) mouse model is one of the most reliable and consistent inbred strains used in biomedical research. Known for its uniform genetic makeup, the C57BL/6 strain is ideal for …

This unique characteristic makes these mice ideal for creation of novel strains with targeted mutations (gene knockouts). B6 albino mice are used to generate blastocysts that can be used …

Separate breeding colonies of C57BL/6 (“B6”) mice maintained at the Jackson Laboratories (“J”) and NIH (“N”) have led to the emergence of two distinct substrains of C57BL/6 mice: …