Apr 25, 2022 · 10 - 20% of women with ASCUS are proven to have underlying high grade squamous intraepithelial lesion (HSIL) (Am J Obstet Gynecol 2003;188:1383) 5 year risks for HSIL and cancer: ASCUS with negative HPV, 1.1%; ASCUS with positive HPV, 18% (N Engl J Med 2013;369:2324)

Jan 31, 2022 · Atypical squamous cells of undetermined clinical significance (ASCUS): Nuclei approximately 2.5 - 3x the area of the nucleus of a normal intermediate squamous cell or 2x the size of a squamous metaplastic cell nucleus Slightly increased N/C ratio Minimal nuclear hyperchromasia and irregular chromatin distribution or nuclear shape

Jan 31, 2023 · Initially endorsed in 2001 as triage test for ASCUS (ASC of undetermined significance) cytologic result Approved for: Cotesting in 2003 Postcolposcopic / posttreatment follow up and risk stratification using partial genotype (HPV 16/18) in 2006 Primary screening option in 2014 5 FDA approved HPV testing platforms: Qiagen Hybrid Capture

Nov 6, 2006 · May cause increased incidence of ASCUS in Pap smears of peri- and post-menopausal women (Cancer 2001;93:100) Associated with scanty smears (Cytopathology 1997;8:274), ASCUS in postmenopausal women (Diagn Cytopathol 2001;24:132) Changes may disappear after topical estrogen

Mar 29, 2021 · A 32 year old woman presented after 2 consecutive Pap tests revealing atypical squamous cells of undetermined significance (ASCUS). Colposcopic exam was unsatisfactory. Loop electrosurgical excision procedure (LEEP) was performed and showed the histologic findings in the image above.

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Dec 8, 2023 · Initially endorsed as triage test for ASCUS cytologic result in 2001 Approved for: Cotesting in 2003 Postcolposcopic / posttreatment follow up and risk stratification using partial genotype (HPV 16 / 18) in 2006 Primary screening option in 2014 5 FDA approved HPV testing platforms: Qiagen Hybrid Capture Hologic Cervista Hologic Aptima

A-E: actinomycosis adenocarcinoma in situ adenoid basal carcinoma adenoid cystic carcinoma adenomyoma adenosarcoma adenosquamous carcinoma alveolar soft part sarcoma anatomy Arias Stella reaction ASC-H (cytology) ASCUS (cytology) atrophy atypical glandular cells (cytology) atypical polypoid adenomyoma bacterial vaginosis bethesda system blue ...

Jan 24, 2025 · Can be categorized as LSIL, HSIL or atypical squamous cells of uncertain significance (ASCUS) LSIL: hyperchromasia, nuclear irregularity, koilocytotic atypia and > 3 fold nuclear enlargement compared to superficial squamous cells

Oct 12, 2021 · LSIL is a heterogenous group caused by Low risk HPV: 6, 11, 42 and 44 High risk HPV: 16, 18, 31, 33, 35, 45, 52 and 58