JNK/PI3K/Akt signaling pathway is involved in myocardial …
Jun 15, 2016 · The present study was designed to investigate whether inhibiting JNK activity would partially restore the PI3K/Akt signaling pathway and protect against myocardial I/R …
The phosphatidylinositol 3-kinase/Akt and c-Jun N-terminal …
The phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway and c-Jun N-terminal kinase (JNK) pathway are responsible for regulating a variety of cellular processes including cell growth, …
JNK/PI3K/Akt signaling pathway is involved in myocardial …
Recent studies have demonstrated that diabetes impairs the phosphatidylinositol 3-kinase/Akt (PI3K/Akt) pathway, while insulin resistance syndrome has been associated with alterations of …
The phosphatidylinositol 3-kinase/Akt and c-Jun N-terminal …
In this review, we first summarized the functional characteristics, signal transduction and activation mechanisms of the PI3K/Akt and JNK pathways, and then discussed the dual roles …
JNK-Dependent Stat3 Phosphorylation Contributes to Akt …
In the present study, we describe a novel signaling axis of the c-Jun NH2 kinase (JNK) and signal transducer and activator of transcription 3 (Stat3) and its involvement in As 3+ -induced Akt …
AKT is indispensable for coordinating Par-4/JNK cross talk in …
May 22, 2017 · Schematic representation of the regulation of p21 by 3-AWA. 3-AWA induces Par-4 and stimulates ER stress-mediated activation of JNK. The simultaneous inhibition of AKT by …
Activation of the Stress Response Kinase JNK (c-Jun N-terminal …
One potential mechanism responsible for attenuated Akt phosphorylation is activation of JNK, which has been implicated in the development of complications associated with type 2 diabetes .
Modulating phosphatase DUSP22 with BML-260 ameliorates …
1 day ago · JNK inhibitor and BML-260 treatment together produced similar effects on Dex-induced myotube atrophy compared to SP600125 or BML-260 alone (Appendix Fig. S6). ...
Akt2 Negatively Regulates Assembly of the POSH-MLK-JNK …
Nov 28, 2003 · The pro-survival effects of Akt are likely to be mediated in part through its regulation of the c-Jun N-terminal kinase (JNK) signaling pathway. The JNK signaling pathway …
Activation of Akt and JNK/Nrf2/NQO1 pathway contributes to the ... - PubMed
We demonstrated that COP up-regulated phase II antioxidant enzymes NAD (P)H/quinone oxidoreductase 1 (NQO1) through activating the nuclear factor erythroid-2 related factor 2 …
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