
Screening and mechanism of six angiotensin I-converting eneyme ...
Oct 1, 2023 · Angiotensin I-converting eneyme (ACE) containing a Zn 2+ cofactor, also known as kinase II or peptidyl-carboxypeptidase, that plays an important role in the regulation of the human blood pressure system (Vásquez, Zapata, Chamorro, Fillería, & Tironi, 2022).
Effective treatment of hypertension by recombinant
Dec 21, 2015 · Angiotensin-converting enzyme inhibitory peptides (ACEIPs), which are made from tuna frame protein (TFP) and yellow fin sole frame protein (YFP), have been used previously to treat hypertension.
Angiotensin-converting enzyme inhibitory peptide attenuates …
Jun 1, 2023 · We found that ACEIP significantly improved diastolic dysfunction as reflected by the increase in mitral inflow E and A wave ratio (E/A ratio) and decrease in isovolumic relaxation time (IVRT). Meanwhile, LV Mass, IVS, LVPW and LVD in systolic or diastolic period were significantly reduced by ACEIP.
Identification and in silico screening of novel angiotensin …
Oct 1, 2024 · Angiotensin-converting enzyme (ACE) inhibitory peptides (ACEIPs) have garnered enormous attention in maintaining blood pressure balance of humans. In this study, the amino acid sequence of Pacific saury ultrafiltration fraction was identified by …
Journal of Agricultural and Food Chemistry - ACS Publications
Nov 4, 2024 · Some food-derived peptides can suppress ACE, named ACEIP with fewer undesirable effects. Therefore, it is crucial to seek strong dietary ACEIP to aid in hypertension treatment. In this article, we propose a new model called AI4ACEIP to identify ACEIP.
Protective effect of recombinant Lactobacillus plantarum against …
May 5, 2021 · Expression of the hypertension-related protein (AngII protein) in HUVEC cells protected by NC8-pSIP409-alr-ACEIP decreased and expression of ACE2 protein increased. These plantarum results suggested that NC8-pSIP409-alr-ACEIP protects against H 2 O 2 -induced injury in HUVEC cells.
Angiotensin I-converting enzyme inhibitory peptide: an …
May 31, 2022 · We provide a comprehensive update of the ACE-Ang II-G protein-coupled type 1 angiotensin receptor (AT1R) axis signaling and its functional significance for potential translation into...
ACE inhibitor - Wikipedia
Frequently prescribed ACE inhibitors include benazepril, zofenopril, perindopril, trandolapril, captopril, enalapril, lisinopril, and ramipril. ACE inhibitors were initially approved for the treatment of hypertension and can be used alone or in combination …
Aceon: Side Effects, Uses, & Warnings - Drugs.com
Aug 22, 2023 · ACE stands for angiotensin converting enzyme. Aceon is used to treat high blood pressure (hypertension) and to prevent heart attack in people with coronary artery disease. Aceon may also be used for purposes not listed in this medication guide. Do not Aceon use if …
Hydrolyzates of silkworm pupae (Bombyx mori) protein is a new
The predicted inhibitory activity of hydrolyzates on ACE was 73.5 % at a concentration of 2.0 mg/ml. Optimized RSM technique decreased IC(50) of hydrolyzates inhibiting ACE to 1.4 mg/mL from 2.5 mg/ml.