In many multicellular organisms, oxygen is transported by respiratory proteins, which are globins in vertebrates, between respiratory organs and tissues. In jawed vertebrates, eight globins are known which are expressed in a highly tissue-specific manner.

Jul 7, 2011 · Spectroscopic analysis and ligand binding kinetics of recombinant chicken GbE reveal a penta-coordinated globin with an oxygen affinity of P50 = 5.8 torrs at 25 °C and 15 torrs at 41 °C. Together these data suggest that GbE helps …

The globins are a superfamily of heme -containing globular proteins, involved in binding and/or transporting oxygen. These proteins all incorporate the globin fold, a series of eight alpha helical segments. Two prominent members include myoglobin and hemoglobin. Both of these proteins reversibly bind oxygen via a heme prosthetic group.

Dec 17, 2004 · While neuroglobin is expressed in the chicken's brain and eye, cytoglobin RNA was detected in all investigated tissues. In addition, a novel globin-type has been identified that is only expressed in the chicken's eye. The gene of this eye-globin contains the typical globin introns at B12.2 and G7.0.

Jul 29, 2011 · Respiratory proteins such as myoglobin may enhance oxygen supply to certain tissues, and thus the mammalian retina harbors high amounts of neuroglobin. Globin E (GbE) was recently identified as an eye-specific globin of chicken (Gallus gallus).

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Dec 17, 2004 · While neuroglobin is expressed in the chicken’s brain and eye, cytoglobin RNA was detected in all investigated tissues. In addition, a novel globin-type has been identified that is only expressed in the chicken’s eye. The gene of this eye-globin contains the typical globin introns at B12.2 and G7.0.

Jun 24, 2011 · Burmester's team used a number of techniques to characterize globin E and found that it is responsible for storing and delivering oxygen to the retina. The finding is intriguing for a number of...

We obtained putative GbE orthologs from the genome assemblies of the turkey M. gallopavo (protein ENSMGAG00000012002) and the zebra finch T. guttata (hypothetical protein LOC100232117, accession...

We have now investigated GLP‐1R expression in normal human eyes and eyes of patients with advanced stages of proliferative DR (PDR) by IHC with the thoroughly validated monoclonal antibody 3F52. The IHC analysis was confirmed by the detection of …