Guaiacol (/ ˈ ɡ w aɪ ə k ɒ l /) is an organic compound with the formula C 6 H 4 (OH)(OCH 3). It is a phenolic compound containing a methoxy functional group. Guaiacol appears as a viscous colorless oil, although aged or impure samples are often yellowish.

Guaiacol is a monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position. It has a role as an expectorant, a disinfectant, a plant metabolite and an EC 1.1.1.25 (shikimate dehydrogenase) inhibitor. It is functionally related to a catechol.

Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma.

Aug 17, 2017 · Dilution of cask whisky (69 vol-% of ethanol) drives taste-contributing compounds such as guaiacol to its surface thus improving the taste. Serious whiskey drinkers insist that it tastes better...

Guaiacol — a GYS inhibitor and a candidate for APBD therapy. Initially used for treating lung abscesses , guaiacol has been used to treat reflux esophagitis and, in combination with codeine (Pulmo Bailly), or as a precursor to guaifenesin (Resyl Syrup), to treat cough. In this work, we show that guaiacol, discovered as a positive hit for PGB ...

As shown in Scheme 1, guaiacol (2-methoxyphenol) is treated with sodium ethoxide to give a sodium salt which is quenched with an epoxyalkene. The final step involves the oxidation of the alkene to the diol using potassium permanganate [4].

Jun 20, 2011 · Guaiacol, or o -methoxyphenol, was first isolated from the tree resin guaiac by A. Sobrero in 1843. Today, it is manufactured by methylating catechol (o -dihydroxybenzene). It is used medically as an expectorant, antiseptic, and local anesthetic; it is also a precursor to flavorants and aromas, including those incorporated in synthetic sandalwood.

Guaiacol is an organic compound known for its distinctive smoky aroma, commonly found in various natural sources and used in flavoring and fragrance industries.

Guaiacol is a plant phenol with myeloperoxidase inhibitor activity (Jayaraj et al.2020). This compound can modulate oxidative stress due to its methoxy substitution in the ortho position, which increases the radical scavenging efficiency of guaiacol (Azadfar et al.2015).

Apr 17, 2023 · Guaiacwood, also known as guaiacwood oil or guaiacol, is a natural aromatic ingredient used in perfume development. Obtained from the wood of the guaiacum officinalis tropical tree, native to South America and the Caribbean, guaiacwood is known for its distinct smoky, woody, and slightly sweet aroma.