
Cre-Lox recombination - Wikipedia
Cre-Lox recombination is a site-specific recombinase technology, used to carry out deletions, insertions, translocations and inversions at specific sites in the DNA of cells. It allows the DNA …
The Cre- loxP System: A Powerful Tool in the Genetic Toolbox
Cre-loxP recombination allows scientists to excise, insert, or invert specific DNA segments with unprecedented accuracy. This works through two key components: a Cre recombinase and …
Mouse Cre-LoxP system: general principles to determine tissue …
Cre- loxP system is a widely used powerful technology for mammalian gene editing. This system has advantages which is very simple manipulation and do not require additional factors for …
LoxP Site - an overview | ScienceDirect Topics
A LoxP site is a specific 34 base pair DNA sequence that is recognized by the Cre recombinase enzyme. It is used to manipulate DNA sequences by inducing deletion or inversion of the …
Addgene: Cre-lox system
The Cre-lox system, derived from P1 bacteriophage, is a potent and specific system for controlling gene expression. The protein Cre recombinase recognizes 34 bp loxP sites, and the …
Cre-loxP-Mediated Recombination: General Principles and Experimental ...
Mar 2, 2017 · The cre-loxP-mediated recombination system (the "cre-loxP system") is an integral experimental tool for mammalian genetics and cell biology. Use of the system has greatly …
Plasmids 101: Cre-lox - Addgene
Jan 13, 2015 · LoxP (locus of X(cross)-over in P1) sites are 34-base-pair long recognition sequences consisting of two 13-bp long palindromic repeats separated by an 8-bp long …
Detecting and Avoiding Problems When Using the Cre/lox System
Cre recombinase (Cre) is a 343-amino-acid protein comprised of 4 subunits that recognizes pairs of specific 34 bp DNA sequences called loxP sites. It initially creates a DNA loop and then …
Cre/ loxP Recombination System and Gene Targeting - Springer
In addition to the generation of subtle mutations, this system allows for a number of other genotypic options in ES cells or mice by strategically incorporating Cre recombinase …
Cre-Lox Recombination System & Conditional Mouse Models
Oct 20, 2020 · Cyclization recombinase (Cre) is one of the tyrosine site-specific recombinases, which is known to catalyse the site specific recombination event between two DNA recognition …