Wnt signaling pathway - Wikipedia
In cellular biology, the Wnt signaling pathways are a group of signal transduction pathways which begin with proteins that pass signals into a cell through cell surface receptors. The name Wnt, …
Wnt target genes and where to find them - PMC - PubMed …
We define “direct Wnt targets” as genes whose regulatory DNA can be physically associated with T-cell factors (TCFs) or other transcription factors (TFs) and whose expression is modulated …
Wnt/β-catenin signalling: function, biological mechanisms, …
Jan 3, 2022 · Acute liver injury induced by carbon tetrachloride leads to activation of the Wnt/β-catenin signalling pathway, which manifests as an increase in the level of the Wnt target gene …
Wnt signal transduction pathways - PMC - PubMed Central (PMC)
The Wnt signaling pathway is an ancient and evolutionarily conserved pathway that regulates crucial aspects of cell fate determination, cell migration, cell polarity, neural patterning and …
The Wnt Homepage
Jan 1, 2025 · Wnt signaling is often implicated in stem cell control, as a proliferative and self-renewal signal. Mutations in Wnt genes or Wnt pathway components lead to specific …
The origin and evolution of Wnt signalling - Nature
Feb 19, 2024 · In this Review, we summarize the current state of research regarding the evolutionary origin of Wnt signalling, its ancestral function and the characteristics of the primal …
Wnt signaling pathways in biology and disease: mechanisms and ...
Apr 4, 2025 · Given its pivotal role in cellular communication, aberrant Wnt signaling has been extensively linked to the pathogenesis of various diseases. This review offers an in-depth …
Wnt signaling in cancer: from biomarkers to targeted therapies …
Apr 2, 2025 · Adenomatous polyposis coli (APC) APC is a tumor suppressor gene that regulates β-catenin degradation [65, 66].However, alterations in the APC gene impair Wnt signaling …
The Wnt Homepage - Stanford University
Jan 1, 2025 · Wnt signaling is often implicated in stem cell control, as a proliferative and self-renewal signal. Mutations in Wnt genes or Wnt pathway components lead to specific …
The Wnts - PMC - PubMed Central (PMC)
Mar 1, 2001 · The Wnt genes encode a large family of secreted protein growth factors that have been identified in animals from hydra to humans. In humans, 19 WNT proteins have been …