Study 1 strengths include carefully controlled exposure to nicotine vs. placebo e-cigarettes, and the novel comparison of placebo versus a no e-cigarette condition to test simple behavioral effects of e-cigarette use.

Sep 24, 2024 · This randomized, double-blinded, placebo-controlled study investigated the effect of nicotine mouth spray on urges to vape in healthy exclusive vapers who had abstained from vaping overnight before study treatment administration.

Findings suggest that cognitive expectancies contribute to the acute effects of e-cigarettes on craving, which may provide guidance for their potential as smoking cessation aids. Keywords: e-cigarette, cigarette, smoking, expectancies, balanced-placebo, nicotine.

Nicotine mouth spray showed statistically significant reductions in urges to vape as soon as 30 seconds and up to 2 hours after dosing compared with placebo, and nicotine mouth spray was well-tolerated and safe.

The independent and synergistic influences of drug and expectancies were parsed using a balanced-placebo design, whereby 128 participants (52 dual users) were provided an e-cigarette that either contained nicotine or non-nicotine solution, while told that it …

The current study investigated the separate and combined effects of nicotine delivery and outcome expectancies on cravings for cigarettes and e-cigarettes using a balanced-placebo experiment.

Jan 1, 2021 · Mean arterial pressure increased in the nicotine condition during VAPE and remained elevated during REC (6.5 ± 1.6 mmHg nicotine vs. 2.6 ± 1 mmHg placebo, during VAPE and 4.6.0 ± 1.7 mmHg nicotine vs. 1.4 ± 1.4 mmHg placebo, during REC; P < 0.05).

Keywords : e-cigarette, cigarette, smoking, expectancies, balanced -placebo , nicotine Public Health Impact : This study demonstrated that use of an electronic cigarette may reduce nicotine craving (i.e., desir e to smoke or vape) via nonpharmacological routes, including beliefs

This randomized, double‐blinded, placebo‐controlled study investigated the effect of nicotine mouth spray on urges to vape in healthy exclusive vapers who had abstained from vaping overnight before study treatment administration.

May 16, 2024 · This randomized, double-blind, placebo-controlled, 2-site (Yale and MUSC) preliminary clinical trial of varenicline (daily titration to 2 mg, FDA-approved for smoking cessation) investigated its potential for e-cigarette cessation in adults who reported exclusive daily use for ≥6 months and no other past 30-day tobacco use (N=40) (see ...