VDAC1 - Wikipedia
Voltage-dependent anion-selective channel 1 (VDAC-1) is a beta barrel protein that in humans is encoded by the VDAC1 gene located on chromosome 5. [4][5] It forms an ion channel in the …
VDAC1 Gene - GeneCards | VDAC1 Protein | VDAC1 Antibody
Mar 30, 2025 · Complete information for VDAC1 gene (Protein Coding), Voltage Dependent Anion Channel 1, including: function, proteins, disorders, pathways, orthologs, and expression.
Mitochondrial VDAC1: A Key Gatekeeper as Potential Therapeutic …
VDAC1 is the gatekeeper for the passages of metabolites, nucleotides, and ions; it plays a crucial role in regulating apoptosis due to its interaction with apoptotic and anti-apoptotic proteins, …
VDAC1 at the Intersection of Cell Metabolism, Apoptosis, and …
The voltage-dependent anion channel 1 (VDAC1) protein, is an important regulator of mitochondrial function, and serves as a mitochondrial gatekeeper, with responsibility for …
VDAC1 at the crossroads of cell metabolism, apoptosis and cell …
This review presents current knowledge related to VDAC1 as a multi-functional mitochondrial protein acting on both sides of the coin, regulating cell life and death, and highlighting these …
VDAC1 voltage dependent anion channel 1 [ (human)]
Data show that voltage-dependent anion channel 1 (VDAC1) knockout cells are resistant to AMP-activated protein kinase (AMPK) and mechanistic target of rapamycin (mTOR) modulation by …
VDAC1-interacting molecules promote cell death in cancer …
The overexpression of VDAC1 in highly glycolytic cancer cells prompted us to develop a workflow for the identification of chemical entities able to decrease energy production in cancer cells. …
VDAC1: A Key Player in the Mitochondrial Landscape of ... - PubMed
Dec 30, 2024 · Voltage-Dependent Anion Channel 1 (VDAC1) is a mitochondrial outer membrane protein that plays a crucial role in regulating cellular energy metabolism and apoptosis by …
Mitochondrial VDAC1: A Potential Therapeutic Target of ... - MDPI
Oct 10, 2022 · VDAC1 mediates the release of mtDNA into the cytoplasm to enhance cytokine levels by activating immune responses. VDAC1 regulates mitochondrial Ca2+ transportation, …
VDAC1 functions in Ca2+ homeostasis and cell life and death in …
In the outer mitochondrial membrane (OMM), the voltage-dependent anion channel 1 (VDAC1) serves as a mitochondrial gatekeeper, controlling the metabolic and energy cross-talk between …