Tumor necrosis factor, alpha-induced protein 3 or A20 is a protein that in humans is encoded by the TNFAIP3 gene. [5][6] This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF).

Mar 30, 2025 · TNFAIP3 (TNF Alpha Induced Protein 3) is a Protein Coding gene. Diseases associated with TNFAIP3 include Autoinflammatory Syndrome, Familial, Behcet-Like 1 and Familial Behcet-Like Autoinflammatory Syndrome. Among its related pathways are TNF signaling and Metabolism of proteins.

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Jul 15, 2021 · Objective: To study long-term outcomes in patients with CNS demyelinating events exposed to TNFa-inhibitors (TNFai), including subsequent clinical relapse, MRI lesions, and use of disease modifying therapy (DMT) for MS.

May 25, 2023 · All TNFAIs and most ILIs demonstrated significantly elevated tuberculosis RORs (Table I). Our study demonstrates a relatively lower tuberculosis association for etanercept and a significant safety signal for infliximab (Tables I and II).

Background: TNF alpha inhibitor (TNFAI) therapy has been associated with inflammatory neurological syndromes. Objectives: To present 10 new cases of TNFAI associated neurological disease and a review of the literature.

Dec 8, 2020 · TNF-a inhibitors (TNFai) were introduced more than 20 years ago and have the most well-reported PRs. TNFai are approved in dermatology for the treatment of psoriasis and hidradenitis suppurativa and used off label in other settings. Common uses in other disciplines include inflammatory bowel disease (IBD), rheumatoid arthritis, and spondyloar ...

This case series highlights the gaps for which prospective trials are needed to identify ideal TNFai initiation timing (upfront versus third line) and dosing, optimal patient selection, and relevant treatment endpoints in isolated CS.

Tumor necrosis factor alpha inhibitor (TNFai) biologic therapy carries the highest risk for histoplasmosis infection after epidemiological exposure, so other IM are preferred during active histoplasmosis infection.

Medical TNFAI abbreviation meaning defined here. What does TNFAI stand for in Medical? Get the most popular TNFAI abbreviation related to Medical.