This repository employs a deep-learning method for the automated segmentation of total metabolic tumor volume (TMTV) in whole-body [18]F-FDG PET/CT images, with an emphasis on multi-center generalizability.

Introduction: Baseline 18F-FDG PET/CT image-driven features have shown predictive values in Diffuse Large B-cell lymphoma (DLBCL) patients. Notably, total metabolic active tumor volume (TMTV) and tumor dissemination (Dmax) have shown predictive values to characterize tumor burden and dissemination.

Feb 6, 2022 · This generic deep learning model to compute TMTV in lymphomas can drastically reduce computation time of TMTV. The total metabolic tumor volume (TMTV) is a new prognostic factor in lymphomas that could benefit from automation with deep learning convolutional neural networks (CNN).

Our model, TMTV-Net, is specifically designed to automate TMTV segmentation from PET/CT scans. TMTV-Net demonstrates robust performance and adaptability in TMTV segmentation across diverse multi-site external datasets, encompassing various lymphoma subtypes.

Feb 8, 2024 · TMTV-Net demonstrates strong performance and generalizability in TMTV segmentation across multi-site external datasets, encompassing various lymphoma subtypes.

May 1, 2023 · We highlight advancements in the role of neural networks for performing automated image segmentation to calculate PET-based imaging biomarkers such as the total metabolic tumor volume (TMTV).

Feb 8, 2024 · Purpose Total metabolic tumor volume (TMTV) segmentation has significant value enabling quantitative imaging biomarkers for lymphoma management. In this work, we tackle the challenging task...

In this study, we propose a two-step cascaded segmenta-tion approach to facilitate TMTV quantification and efec-tively handle the variability in lesion sizes and locations in lymphoma cases.

Mar 1, 2024 · Artificial intelligence (AI) offers a solution for automating TMTV measurement, thereby enhancing its clinical utility. This study aimed to develop and clinically evaluate a deep-learning-based image segmentation algorithm for automatic TMTV measurement in metastatic non-small cell lung cancer (NSCLC) patients.

Feb 6, 2022 · The total metabolic tumor volume (TMTV) is a new prognostic factor in lymphomas that could benefit from automation with deep learning convolutional neural networks (CNN). Manual TMTV...