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Apr 16, 2020 · High baseline TMTV (±ECOG) was a strong prognosticator of inferior PFS and OS in REMARC patients post-R-CHOP, irrespective of maintenance. Early identification of ultra-risk diffuse large B-cell lymphoma (DLBCL) patients is needed to …

Mar 20, 2025 · TMTV measured with the SUV4.0 threshold provides a comparable PFS prediction than the 41%SUVmax method supporting its routine adoption particularly in the diffuse large B cell lymphoma subtype.

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The total metabolic tumor volume (TMTV) was computed using the 41% SUV max method. Results: With a median follow-up of 6.5 years, the 6-year progression-free survival (PFS) was 57.8%, the median TMTV was 284 cm 3, SUV max was 11.3 and SD max was 0.32 m-1, with no significant difference between arms.

Feb 1, 2017 · The purpose of this study was to compare in a large series of peripheral T cell lymphoma, as a model of diffuse disease, the prognostic value of baseline total metabolic tumor volume (TMTV) measured on 18F-FDG PET/CT with adaptive thresholding methods with TMTV measured with a fixed 41% SUVmax threshold method.

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Aug 1, 2022 · The percentage of patients with high TMTV (Q4) at baseline was 45% in the primary chemorefractory population, 49% in the POD12 population, and 21% to 22% in the non-chemorefractory/no-POD12 event populations.

Nov 5, 2024 · Total metabolic tumor volume (TMTV) derived from positron emission tomography/computed tomography (PET/CT) data has been shown to serve as an accurate tumor burden surrogate and be associated with outcomes in FL (Cottereau et al. Ann Oncol 2024).