High baseline TMTV (±ECOG) was a strong prognosticator of inferior PFS and OS in REMARC patients post-R-CHOP, irrespective of maintenance. Early identification of ultra-risk diffuse large B-cell lymphoma (DLBCL) patients is needed to aid stratification to innovative treatment.

Among experts who deemed PET-CT relevant at baseline, they elected the total metabolic tumor volume (TMTV) as most interesting prognostic marker (n = 25, 34%), before the maximum standardized uptake value (SUVmax) of the main lesion …

One such parameter is total metabolic tumor volume (TMTV), which is the total 3-dimensional volume of all FDG-avid lesions on PET-CT. 25, 34 TMTV has been found in 1 study to be an independent predictor of outcome in grade 1 to 3 high tumor burden FL, 35 but not predictive of outcome in another study of favorable grade 1 to 2 FL. 36 A second ...

Sep 3, 2024 · Total metabolic tumor volume (TMTV) is prognostic in lymphoma. However, cutoff values for risk stratification vary markedly, according to the tumor delineation method used. We aimed to create a standardized TMTV benchmark dataset allowing TMTV to be tested and applied as a reproducible biomarker.

Based on our TMTV measurements, a value of 25 ml in PET-0 suits well for an optimal discrimination between patients with CMR and non-CMR in PET-1. All patients with a TMTV ≤ 25 ml in PET-0 achieved CMR in PET-1, whereas only …

Aug 1, 2024 · Total metabolic tumor volume (TMTV) is prognostic in lymphoma. However, cutoff values for risk stratification vary markedly, according to the tumor delineation method used. We aimed to create a standardized TMTV benchmark dataset allowing TMTV to be tested and applied as a reproducible biomarker.

Jul 28, 2020 · Total metabolic tumor volume (TMTV) is a promising quantitative biomarker for therapy assessment and prognosis in Hodgkin Lymphoma affected patients that allows prediction of patient...

Jan 17, 2024 · Our study demonstrates that the integration of TMTV on baseline 18 F-FDG PET/CT with EGFR mutation status improves the accuracy of prognostic evaluation for patients with LUAD. Keywords: Lung adenocarcinoma, Metabolic tumor volume, Epidermal growth factor receptor, 18F-2-fluoro-2-deoxyglucose, Positron emission tomography, Computed tomography.

Jan 13, 2023 · Te mostramos en este programa un resumen de actividades que tuvieron lugar en Posadas y también en la provincia. Misiones tiene mucho por descubrir y lo hacemos juntos.

Dec 16, 2024 · We aimed to explore the predictive value of total metabolic tumor volume (TMTV) and beta-2-microglobulin (B2M) levels in patients with follicular lymphoma (FL) with a high tumor burden receiving standard first-line immunochemotherapy.