TNK-tPA (tenecteplase) is an injection that dissolves blood clots in certain blood vessels in your body. Blood clots happen when your blood thickens. A healthcare provider will give you this injection in a hospital or clinic setting.

Tenecteplase is a thrombolytic (THROM-bo-LIT-ik) drug, sometimes called a "clot-busting" drug. It helps your body produce a substance that dissolves unwanted blood clots. Tenecteplase is used to prevent death in people who have had a heart attack (acute myocardial infarction).

TNKase (tenecteplase) is indicated for the treatment of acute ischemic stroke (AIS) in adults. TNKase is contraindicated in any patients with: TNKase is also contraindicated in patients for the treatment of AIS with: TNKase can cause significant, sometimes fatal, internal or external bleeding, especially at arterial and venous puncture sites.

Oct 1, 2024 · Tenecteplase (TNK) can help dissolve blood clots to treat acute ischemic stroke. Learn about how it works, when doctors administer it, and more.

Tenecteplase (TNK) is a single-bolus recombinant fibrinolytic agent used to manage intravascular clots. The drug is in the tissue plasminogen activator (tPA) class of medications. FDA-approved indications include acute ST-elevation myocardial infarction (STEMI).

During and following TNKase administration for the treatment of AIS, frequently monitor and control blood pressure 1; In patients without recent use of oral anticoagulants or heparin, TNKase treatment can be initiated prior to the availability of coagulation study results.

TNK-tPA, Metalyse, TNKase, Elaxim. It comes in a set-up not-unlike Prothrombinex with a diluent and a transfer device. Don’t shake it up, swirl gently. It enhances the conversion of plasminogen to plasmin by binding to fibrin initiating fibrinolysis with limited systemic proteolysis.

Oct 13, 2020 · Tenecteplase is a type of tPA (tissue-type plasminogen activator) of increasing interest for the thrombolytic treatment of acute ischemic stroke due to advantageous drug characteristics and ease of administration.

Jun 14, 2024 · Tenecteplase is an effective thrombolytic agent for eligible patients with stroke who are treated within 4.5 hours after the onset of stroke. However, data regarding the effectiveness of...

Mar 11, 2025 · TNKase® (tenecteplase) for injection, for intravenous ... 1.1 Acute Ischemic Stroke - TNKase is indicated for the treatment of acute ischemic stroke (AIS) in adults. 1.2 Acute ST Elevation Myocardial Infarction - TNKase is indicated to reduce the ...